| Protein: | Top3beta-PA, FBp... |
| Organism: | Drosophila melanogaster |
| Length: | 875 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Top3beta-PA, FBp....
| Description | E-value | Query Range |
Subject Range |
|
|
674.0 | [0..1] | [875..95] |
|
Region A: Residues: [1-599] |
1 11 21 31 41 51
| | | | | |
1 MKSVLMVAEK PSLAASLAGI LSNGRCTAKR GTGNGCSTHE WTGNFRNEGS VHFRMTSVCG 60
61 HVMSLDFNKK YNCWDKVDPI QLFGCATEKK ETNPKQNMRK FLAHEARGCD YLVLWLDCDK 120
121 EGENICFEVM DAVKHVINNV YSDQVTYRAH FSAITEKDIK KAMETLGHPN ENEAKSVDAR 180
181 QELDLRIGCA FTRFQTKFFQ DRYGDLDSSL ISYGPCQTPT LGFCVKRHDD IQTFKPESFW 240
241 HLQLLAGQPE VTLEWARGRV FKKDIAIMLL NRVKEHKKAT VESVASKEAY KSKPQALNTV 300
301 ELMRICSSGL GIGPFQAMQI AERLYTQGYI SYPRTETNQY PTNFDLPAVL HVLKPSADFG 360
361 EEARSILGDI QTPRKGKDAG DHPPITPMKL GNRSDFDRDT WRVYEFICRH FMGTVSRDLK 420
421 YRVTTAKLSV GMETFSCTAS VLIDAGFTKV MTWSAFGKDE PQPPFVQGTQ VAINDVRLIE 480
481 SQTGPPDYLT ESELITLMEE HGIGTDASIP VHINNICQRN YVHIENGRKL MPTTLGIVLV 540
541 HGYQKIDPEL VLPTMRTEVE RMLTLIAQGS ANFQDVLRHA IKIFKLKFMY FVKNIDSMD
|
| Detection Method: |  |
| Confidence: | 172.0 |
| Match: | 1eclA |
| Description: | AMINO TERMINAL 67KDA DOMAIN OF ESCHERICHIA COLI DNA TOPOISOMERASE I (RESIDUES 2-590 OF MATURE PROTEIN) CLONING ARTIFACT ADDS TWO RESIDUES TO THE AMINO-TERMINUS WHICH WERE NOT OBSERVED IN THE EXPERIMENTAL ELECTRON DENSITY (GLY-2, SER-1). |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA topoisomerase activity | 10.2798831210729 | bayes_pls_golite062009 |
| DNA topoisomerase type I activity | 8.04585827786358 | bayes_pls_golite062009 |
| isomerase activity | 5.61256457337998 | bayes_pls_golite062009 |
| DNA binding | 5.20730175008144 | bayes_pls_golite062009 |
| nucleic acid binding | 4.95671919332271 | bayes_pls_golite062009 |
| binding | 4.3089127577748 | bayes_pls_golite062009 |
| catalytic activity | 1.50449367975676 | bayes_pls_golite062009 |
| hydrolase activity | 0.715654828097203 | bayes_pls_golite062009 |
| protein binding | 0.377429709958808 | bayes_pls_golite062009 |
|
Region A: Residues: [600-698] |
1 11 21 31 41 51
| | | | | |
1 ALFEVSFSPL AESGKAHSRC GKCRRYMKYI QTKPARLHCS HCDETYALPI GNVKVYREFK 60
61 CPLDDFDLLA FSTGVKGRSY PFCPYCYNHP PFSDMPHLG
|
| Detection Method: | |
| Confidence: | 1.02 |
| Match: | 2fe3A |
| Description: | No description for 2fe3A was found. |
|
Region A: Residues: [699-875] |
1 11 21 31 41 51
| | | | | |
1 GCNTCTNANC PHSLNTLGIS SCVECPTGVL VLDCTLAPTW KLGCNRCDVI INCFKGATKI 60
61 TVEEAKCQEC GAQQVNVVYK SDKSKFKDGS EEKSGCIFCS ADFSHLVEKH RAVASRPVRS 120
121 GGGFRGGKAG RGGGGMGGAA FGSGGAVTAG GGPNAGGGVR GSRVAKDKMG QLASYFV
|
| Detection Method: | |
| Confidence: | 34.09691 |
| Match: | 2i13A |
| Description: | No description for 2i13A was found. |
