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View Structure Prediction Details

Protein: gi|22831636, gi|...
Organism: Drosophila melanogaster
Length: 595 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|22831636, gi|....

Description E-value Query
Range
Subject
Range
gi|2293383 - gi|2293383|emb|CAB10912.1| EG:114E2.2 [Drosophila melanogaster]
284.0 [0..1] [578..1]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNSVTPASN TTSLPTSTPS VTTSPPASTD FMLLAAAATS ATSATPATAT SAAATAASNP  60
   61 AKRKLSSIAE IPSKFLVVSD AKGVYSAHTH PNGFAADSLG VDNNETMIKK LMQNLQSQRQ 120
  121 QQSLQQLRSL RPAEISLTP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [140-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPAATRKVDI SNSRTRSYSL SNVSAARDQQ DHPQHQQHAN HMQIQQHYGY MRSNIGGVIY  60
   61 GLHKDSADSA ASSACGAGAG AAAVGMSIAS SAPAAGSQLS AHHHTGHGGR RRTTSSNSN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [259-343]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAGTREVHNK LEKERRAQLK ECYDLLKKVL PMGDEDRKKT SNLTILDTAH KYVNSLSHEV  60
   61 CEQEAKIEKL AKQKIELQKR LKQLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.39794
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.12507195426228 bayes_pls_golite062009
nucleic acid binding 0.43204604575196 bayes_pls_golite062009
DNA binding 0.40884226851256 bayes_pls_golite062009
transcription regulator activity 0.31759335140578 bayes_pls_golite062009
transcription factor activity 0.09721565916723 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [344-595]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRRESPPTDQ QIIPQADKVC LATTATTAPP TAASGHNGTT ILFDAGNACA TGQLTTVINK  60
   61 TNGGATAAAS SKHNGNHTGG ATTTLTPAMG IMTIKNGNGS NGNMLAISPT GGHNHQLHQH 120
  121 HNGSPAGSPS GIGATTGATI TRGSPTPSTP SPSPSSSSSG VSLSTSFMGG SSSSSSSSSS 180
  181 SSSSSSSSSS SSPTQQQQII TPTATARSVG LKFHGGAGAA VPAGGGSVNG FHQADKDRNY 240
  241 TFLRLSAGTT AQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1y0fB
Description: No description for 1y0fB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle