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View Structure Prediction Details

Protein: ph-d-PA
Organism: Drosophila melanogaster
Length: 1537 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ph-d-PA.

Description E-value Query
Range
Subject
Range
gi|17389416 - gi|17389416|gb|AAH17748.1| PHC1 protein [Homo sapiens]
299.0 [0..1097] [1530..6]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHGFGAAPS VSVSGDTESE SATTIRTPPP SPEATTSVKV NSTTRVDPQR PLRCLETLAQ  60
   61 KAGISFDED

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [70-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FAKSPSQSPS SKAARGSVGT PSIRRRHPLL PLSSRSPSAP DSKTTGRKLE KSQSPAQQVA  60
   61 AAT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [133-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVPLQISPEQ LQQLYANNPY AIQVKQEFPT HTTSGSGTEL KHATNIMEVQ QQLQLQQQLS  60
   61 EANGGGAASA GAGGAASPAN SQQSQQQQHS TAISTMSPMQ LAAATGGVGG D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [244-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WTQGRTVQLM QPSTSFLYPQ MIVSGNLLHP GGLGQQPIQV ITAGKPFQGN GPQMLTTTTQ  60
   61 NAKQMIGGQA GFAGGNYATC IPSNHNQSPQ TVLISPVNVI SHSPQQQQNL LQSMAAAAQQ 120
  121 QQLTQQQQQQ LNQQQQQLNQ QQQQQQLTAA LAKVGVDAQG KLAQKVVQKV TTTSSTVQAA 180
  181 TGPGSTGSTQ TQQVQQVQQQ QQQTTQTTQQ CVQVSQSTLP VGVGGQSVQT AQLLNAGQAQ 240
  241 QM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [486-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QIPWFWQNAA GLQPFGSNQI ILRNQPDGTQ GMFIQQQPAT QTLQTQQNQI IQCNVTQTPT  60
   61 KARTQLDALA PKQQQQQQQV GTTNQTQQQQ LAVATAQLQQ QQQQLTAAAL QRPGAPVMPH 120
  121 NGTQVRPASS VSTQTAQNQS LLKAKMRNKQ QPVRPALATL KTEIGQVAGQ NKVVGHLTTV 180
  181 QQQQQATNLQ Q

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [677-889]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVNAAGNKMV VMSTTGTPIT LQNGQTLHAA TAAGVDKQQQ QLQLFQKQHI LQQQMLQQQI  60
   61 AAIQMQQQQA AVQAQQQQQQ QVSQQQQVNA QQQQAVAQQQ QAVAQAQQQQ REQQQQVAQA 120
  121 QAQHQQALAN ATQQILQVAP NQFITSHQQQ QQQQLHNQLI QQQLQQQAQA QVQAQVQAQA 180
  181 QQQQQQREQQ QNIIQQIVVQ QSTGATSQQQ QQQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [890-1101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQQQSGQLQL SSVPFSVSPS MTAEDIAGIT SSALQEALSV SGAIFQTTKP ITCSSSTLPT  60
   61 SSVVTITSQS STPLVTSSTV ASMQQAQTQG TQIHQHQQLI SATIAGGSQQ QQQQQQLGLP 120
  121 SLTPTTPSPT TNPILAMTSM MNATVGHLST APPVSVSSTA VTPSSGQLVT LSSASSGGGA 180
  181 GFPATPTKET PSKGPTATLV PIDSPKTPVS GK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1102-1215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTCTTPKSST PATVSASVEA SSSTGEALSN GDASDRSSTP SKGATTPTSK QSNAAVQPPS  60
   61 STIPNSVSGK EEPKLTTCGS LTSATSTSTT TTITNGIGVA RTTASTAVST ASTT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1216-1303]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTSSGTFTTS CTSTTTTTTS SISNGSKDLP KAMIKPNVLT HVIDGFIIQE ANEPFPVTRQ  60
   61 RYADKDVSDE PPKKKATMQE DIKLSGIA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1304-1450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAPGSDMVAC EQCGKMEHKA KLKRKRYCSP GCSRQAKNGI GGVGSGETNG LGTGGIVGVD  60
   61 AMALVDRLDE AMAEEKMQTE SYQTVSDALP IQAATPEVPP ISMPVLAAMS TSSPLSLPLT 120
  121 LPLPIAIAPT VSLPVVSAGV VAPVLAI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1451-1537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSNINGSDR PPISSWSVEE VSNFIRELPG CQDYVDDFIQ QEIDGQALLL LKENHLVNAM  60
   61 GMKLGPALKI VAKVESIKEV PPGDVKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.154902
Match: 1pk1A
Description: Hetero SAM domain structure of Ph and Scm.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.633600780660145 bayes_pls_golite062009
protein binding 0.29861856894481 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle