YRC Public Data Repository - Protein Structure Prediction

Protein:	MED18-PA
Organism:	Drosophila melanogaster
Length:	217 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED18-PA.

Description	E-value	Query Range	Subject Range
gi\|125981473, gi... - gi\|54643051\|gb\|EAL31795.1\| GA13258 [Drosophila pseudoobscura pseudoobscura], gi\|125981473\|ref\|XP_001... gi\|54643051\|gb\|E... - GA13258-PA [Drosophila pseudoobscura], GA13258 [Drosophila pseudoobscura pseudoobscura]	350.0	[0..1]	[217..1]
MED18_ANOGA - Mediator of RNA polymerase II transcription subunit 18 OS=Anopheles gambiae GN=MED18 PE=3 SV=3 gi\|116131351, gi... - gi\|118779820\|ref\|XP_309758.3\| ENSANGP00000012428 [Anopheles gambiae str. PEST], gi\|116131351\|gb\|EAA0...	321.0	[0..6]	[217..6]
MED18_AEDAE - Mediator of RNA polymerase II transcription subunit 18 OS=Aedes aegypti GN=MED18 PE=3 SV=1	314.0	[0..1]	[217..8]
mdt-18 - status:Confirmed UniProt:Q966M5 protein_id:AAK68280.1	299.0	[0..3]	[210..4]
gi\|48095236 - gi\|48095236\|ref\|XP_392263.1\| PREDICTED: similar to Mediator complex subunit 18 CG14802-PA, isoform A...	295.0	[0..2]	[213..3]
MED18_CAEBR - Mediator of RNA polymerase II transcription subunit 18 OS=Caenorhabditis briggsae GN=mdt-18 PE=3 SV=... gi\|157747541 - gi\|157747541\|ref\|XP_001668865.1\| Hypothetical protein CBG12642 [Caenorhabditis briggsae AF16]	289.0	[0..3]	[217..4]
gi\|149024140, gi... - gi\|169234862\|ref\|NP_001108509.1\| hypothetical protein LOC682988 [Rattus norvegicus], gi\|165971258\|gb... tr\|G3H1Z1\|G3H1Z1... - Mediator of RNA polymerase II transcription subunit 18 OS=Cricetulus griseus GN=I79_004190 PE=4 SV=1	287.0	[0..23]	[213..19]
MED18_MOUSE - Mediator of RNA polymerase II transcription subunit 18 OS=Mus musculus GN=Med18 PE=1 SV=1	286.0	[0..23]	[213..19]
tr\|M3WIT0\|M3WIT0... - Mediator complex subunit 18 OS=Felis catus GN=MED18 PE=4 SV=1 gi\|57044032 - gi\|57044032\|ref\|XP_544460.1\| PREDICTED: similar to mediator of RNA polymerase II transcription, subu...	286.0	[0..23]	[213..19]
MED18_BOVIN - Mediator of RNA polymerase II transcription subunit 18 OS=Bos taurus GN=MED18 PE=2 SV=1	285.0	[0..23]	[213..19]

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Predicted Domain #1

Region A:
Residues: [1-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIVSSARES LSHAMNNRFL PNLEYLLQGS ILDSAVEHLM HRLKGLCDNV DTSPEPFHDL  60
   61 EVCMSLRQPN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [71-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANQPLLLRVR RALGRDAPFQ MRYLGNPEVD LRRPTLVRSC MDCACTNGIL EFLTEMGFRL  60
   61 EFEYIAKGYM FRKGRMKITV SKLIKIVPGK QQDMANEPIS QSYIVELSVV APTGQENVGE 120
  121 EMRVFAEQLK PLVQLEKIDY KRLGGMP

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.21
Match:	2hzmB
Description:	No description for 2hzmB was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits