YRC Public Data Repository - Protein Structure Prediction

Protein:	MED18-PA
Organism:	Drosophila melanogaster
Length:	217 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED18-PA.

Description	E-value	Query Range	Subject Range
gi\|125981473, gi... - gi\|54643051\|gb\|EAL31795.1\| GA13258 [Drosophila pseudoobscura pseudoobscura], gi\|125981473\|ref\|XP_001... gi\|54643051\|gb\|E... - GA13258-PA [Drosophila pseudoobscura], GA13258 [Drosophila pseudoobscura pseudoobscura]	350.0	[0..1]	[217..1]
MED18_ANOGA - Mediator of RNA polymerase II transcription subunit 18 OS=Anopheles gambiae GN=MED18 PE=3 SV=3 gi\|116131351, gi... - gi\|118779820\|ref\|XP_309758.3\| ENSANGP00000012428 [Anopheles gambiae str. PEST], gi\|116131351\|gb\|EAA0...	321.0	[0..6]	[217..6]
MED18_AEDAE - Mediator of RNA polymerase II transcription subunit 18 OS=Aedes aegypti GN=MED18 PE=3 SV=1	314.0	[0..1]	[217..8]
mdt-18 - status:Confirmed UniProt:Q966M5 protein_id:AAK68280.1	299.0	[0..3]	[210..4]
gi\|48095236 - gi\|48095236\|ref\|XP_392263.1\| PREDICTED: similar to Mediator complex subunit 18 CG14802-PA, isoform A...	295.0	[0..2]	[213..3]
MED18_CAEBR - Mediator of RNA polymerase II transcription subunit 18 OS=Caenorhabditis briggsae GN=mdt-18 PE=3 SV=... gi\|157747541 - gi\|157747541\|ref\|XP_001668865.1\| Hypothetical protein CBG12642 [Caenorhabditis briggsae AF16]	289.0	[0..3]	[217..4]
gi\|149024140, gi... - gi\|169234862\|ref\|NP_001108509.1\| hypothetical protein LOC682988 [Rattus norvegicus], gi\|165971258\|gb... tr\|G3H1Z1\|G3H1Z1... - Mediator of RNA polymerase II transcription subunit 18 OS=Cricetulus griseus GN=I79_004190 PE=4 SV=1	287.0	[0..23]	[213..19]
MED18_MOUSE - Mediator of RNA polymerase II transcription subunit 18 OS=Mus musculus GN=Med18 PE=1 SV=1	286.0	[0..23]	[213..19]
tr\|M3WIT0\|M3WIT0... - Mediator complex subunit 18 OS=Felis catus GN=MED18 PE=4 SV=1 gi\|57044032 - gi\|57044032\|ref\|XP_544460.1\| PREDICTED: similar to mediator of RNA polymerase II transcription, subu...	286.0	[0..23]	[213..19]
MED18_BOVIN - Mediator of RNA polymerase II transcription subunit 18 OS=Bos taurus GN=MED18 PE=2 SV=1	285.0	[0..23]	[213..19]

Back

Predicted Domain #1

Region A:
Residues: [1-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIVSSARES LSHAMNNRFL PNLEYLLQGS ILDSAVEHLM HRLKGLCDNV DTSPEPFHDL  60
   61 EVCMSLRQPN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [71-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANQPLLLRVR RALGRDAPFQ MRYLGNPEVD LRRPTLVRSC MDCACTNGIL EFLTEMGFRL  60
   61 EFEYIAKGYM FRKGRMKITV SKLIKIVPGK QQDMANEPIS QSYIVELSVV APTGQENVGE 120
  121 EMRVFAEQLK PLVQLEKIDY KRLGGMP

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.21
Match:	2hzmB
Description:	No description for 2hzmB was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits