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View Structure Prediction Details

Protein: FBpp0308820
Organism: Drosophila melanogaster
Length: 485 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0308820.

Description E-value Query
Range
Subject
Range
gi|73976793 - gi|73976793|ref|XP_857617.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
296.0 [0..3] [470..101]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNADKMQDQ EHDDEQSSDI EGSGDNVGRD DGTDDDDDSN GNMQQENGDG GNGGDGQEHS  60
   61 GDEEQHHSQD NEGNDNSAGQ QQQMQQVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.522879
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.75748736237159 bayes_pls_golite062009
nucleic acid binding 3.30499161454806 bayes_pls_golite062009
mRNA binding 2.67679675039933 bayes_pls_golite062009
binding 2.30438455421982 bayes_pls_golite062009
0.84389121154917 bayes_pls_golite062009
single-stranded RNA binding 0.61170301639809 bayes_pls_golite062009
poly-pyrimidine tract binding 0.40943492051131 bayes_pls_golite062009
protein binding 0.403675976995418 bayes_pls_golite062009
transcription regulator activity 0.361110886317161 bayes_pls_golite062009
mRNA 5'-UTR binding 0.18283446592068 bayes_pls_golite062009
DNA binding 0.139895000724487 bayes_pls_golite062009
translation repressor activity, nucleic acid binding 0.0860748299027598 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [89-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTSATNLIIN YLPQDMTDRE LYNLFSGCGP INTCKIMRDF KTGYSFGYGF VDYKTESDSE  60
   61 DAIQKLNGFY VRNKRLKVSY ARPGGQSIKD TNLYVINLSR NINDDMLDRI FSPYGLIVQR 120
  121 NILRDKLTGR PRGVAFVRYN KREEAQEAIK ALNNTVPEGG SQPIWVRLAE EHGKAKAAQF 180
  181 MAQIGGGNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.09691
Match: 3sxlA
Description: Sex-lethal protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.75748736237159 bayes_pls_golite062009
nucleic acid binding 3.30499161454806 bayes_pls_golite062009
mRNA binding 2.67679675039933 bayes_pls_golite062009
binding 2.30438455421982 bayes_pls_golite062009
0.84389121154917 bayes_pls_golite062009
single-stranded RNA binding 0.61170301639809 bayes_pls_golite062009
poly-pyrimidine tract binding 0.40943492051131 bayes_pls_golite062009
protein binding 0.403675976995418 bayes_pls_golite062009
transcription regulator activity 0.361110886317161 bayes_pls_golite062009
mRNA 5'-UTR binding 0.18283446592068 bayes_pls_golite062009
DNA binding 0.139895000724487 bayes_pls_golite062009
translation repressor activity, nucleic acid binding 0.0860748299027598 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [278-372]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGGGPPHMG PGGPMHPPHH HNNHHHNNHH NPHMPPHHHQ PQHPHQHPQH HPQLHHMQHH  60
   61 HPNNHNNNHP NNHHHNNNNN NHHNMGGPHP HHMQQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [373-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHPMGMNMGM GVNMGMGMGM GMPIHGGGGG GGGGGGGGGG GNFHHMAHRG EVFMLPLPIC  60
   61 SRFPSQPHPV GNGICHSPNK NSRFRLSRRP QASRTTIRYI AHSVADPVPT PTT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.221849
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
eukaryotic initiation factor 4G binding 3.42010690672168 bayes_pls_golite062009
RNA binding 2.72440026355875 bayes_pls_golite062009
mRNA binding 2.69217140436626 bayes_pls_golite062009
single-stranded RNA binding 2.18428706002465 bayes_pls_golite062009
nucleic acid binding 2.17282382736847 bayes_pls_golite062009
poly(A) RNA binding 1.84786464421696 bayes_pls_golite062009
binding 1.42205067775429 bayes_pls_golite062009
poly-purine tract binding 1.35887811843216 bayes_pls_golite062009
catalytic activity 0.658135691360255 bayes_pls_golite062009
protein binding 0.137597344174086 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle