






| Protein: | Appl-PA |
| Organism: | Drosophila melanogaster |
| Length: | 887 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Appl-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
439.0 | [0..1] | [887..1] |
|
Region A: Residues: [1-147] |
1 11 21 31 41 51
| | | | | |
1 MCAALRRNLL LRSLWVVLAI GTAQVQAASP RWEPQIAVLC EAGQIYQPQY LSEEGRWVTD 60
61 LSKKTTGPTC LRDKMDLLDY CKKAYPNRDI TNIVESSHYQ KIGGWCRQGA LNAAKCKGSH 120
121 RWIKPFRCLG PFQSDALLVP EGCLFDH
|
| Detection Method: | |
| Confidence: | 47.39794 |
| Match: | 1mwpA |
| Description: | N-terminal domain of the amyloid precursor protein |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [148-197] |
1 11 21 31 41 51
| | | | | |
1 IHNASRCWPF VRWNQTGAAA CQERGMQMRS FAMLLPCGIS VFSGVEFVCC
|
| Detection Method: | |
| Confidence: | 27.30103 |
| Match: | 1owtA |
| Description: | Amyloid beta a4 protein copper binding domain (domain 2) |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [198-306] |
1 11 21 31 41 51
| | | | | |
1 PKHFKTDEIH VKKTDLPVMP AAQINSANDE LVMNDEDDSN DSNYSKDANE DDLDDEDDLM 60
61 GDDEEDDMVA DEAATAGGSP NTGSSGDSNS GSLDDINAEY DSGEEGDNY
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [307-665] |
1 11 21 31 41 51
| | | | | |
1 EEDGAGSESE AEVEASWDQS GGAKVVSLKS DSSSPSSAPV APAPEKAPVK SESVTSTPQL 60
61 SASAAAFVAA NSGNSGTGAG APPSTAQPTS DPYFTHFDPH YEHQSYKVSQ KRLEESHREK 120
121 VTRVMKDWSD LEEKYQDMRL ADPKAAQSFK QRMTARFQTS VQALEEEGNA EKHQLAAMHQ 180
181 QRVLAHINQR KREAMTCYTQ ALTEQPPNAH HVEKCLQKLL RALHKDRAHA LAHYRHLLNS 240
241 GGPGGLEAAA SERPRTLERL IDIDRAVNQS MTMLKRYPEL SAKIAQLMND YILALRSKDD 300
301 IPGSSLGMSE EAEAGILDKY RVEIERKVAE KERLRLAEKQ RKEQRAAERE KLREEKLRL
|
| Detection Method: | |
| Confidence: | 14.39794 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [666-810] |
1 11 21 31 41 51
| | | | | |
1 EAKKVDDMLK SQVAEQQSQP TQSSTQSQAQ QQQQEKSLPG KELGPDAALV TAANPNLETT 60
61 KSEKDLSDTE YGEATVSSTK VQTVLPTVDD DAVQRAVEDV AAAVAHQEAE PQVQHFMTHD 120
121 LGHRESSFSL RREFAQHAHA AKEGR
|
| Detection Method: | |
| Confidence: | 5.522879 |
| Match: | 1c1gA |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [811-887] |
1 11 21 31 41 51
| | | | | |
1 NVYFTLSFAG IALMAAVFVG VAVAKWRTSR SPHAQGFIEV DQNVTTHHPI VREEKIVPNM 60
61 QINGYENPTY KYFEVKE
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.