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View Structure Prediction Details

Protein: cin-PA
Organism: Drosophila melanogaster
Length: 601 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cin-PA.

Description E-value Query
Range
Subject
Range
gi|505312, gi|10... - gi|505312|gb|AAA65877.1| molybdenum cofactor, gi|1079093|pir||S47896 probable molybdopterin biosynth...
515.0 [0..1] [601..1]

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Predicted Domain #1
Region A:
Residues: [1-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESITFGVLT ISDTCWQEPE KDTSGPILRQ LIGETFANTQ VIGNIVPDEK DIIQQELRKW  60
   61 IDREELRVIL TTGGTGFAPR DVTPEATRQL LEKECPQLSM YITLESIKQT QYAALSRGLC 120
  121 GIAGNTLILN LPGSEKAVKE CFQTISALLP HAVHLIGDDV SLVRKTHAEV QGSAQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.39794
Match: 1jljA
Description: Gephyrin N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.9303555688427 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [177-601]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHICPHKTGT GTDSDRNSPY PMLPVQEVLS IIFNTVQKTA NLNKILLEMN APVNIPPFRA  60
   61 SIKDGYAMKS TGFSGTKRVL GCIAAGDSPN SLPLAEDECY KINTGAPLPL EADCVVQVED 120
  121 TKLLQLDKNG QESLVDILVE PQAGLDVRPV GYDLSTNDRI FPALDPSPVV VKSLLASVGN 180
  181 RLILSKPKVA IVSTGSELCS PRNQLTPGKI FDSNTTMLTE LLVYFGFNCM HTCVLSDSFQ 240
  241 RTKESLLELF EVVDFVICSG GVSMGDKDFV KSVLEDLQFR IHCGRVNIKP GKPMTFASRK 300
  301 DKYFFGLPGN PVSAFVTFHL FALPAIRFAA GWDRCKCSLS VLNVKLLNDF SLDSRPEFVR 360
  361 ASVISKSGEL YASVNGNQIS SRLQSIVGAD VLINLPARTS DRPLAKAGEI FPASVLRFDF 420
  421 ISKYE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 1t3eA
Description: Structural basis of dynamic glycine receptor clustering
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.53018333943857 bayes_pls_golite062009
binding 0.101786434317917 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle