| Protein: | plexA-PB, plexA-PC |
| Organism: | Drosophila melanogaster |
| Length: | 1505 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for plexA-PB, plexA-PC.
| Description | E-value | Query Range |
Subject Range |
|
|
1497.0 | [0..1] | [1505..441] |
|
Region A: Residues: [1-108] |
1 11 21 31 41 51
| | | | | |
1 MFNTKLTSVA ATSTSGYTVV FVGTSDGFLK KVVIESSSIA NEYASFAVDL GSEINRDMQF 60
61 DNQNLYIYVM SKTKVSKVKV FDCSDYKTCG DCLGARDPYC GWCSLENK
|
| Detection Method: |  |
| Confidence: | 24.0 |
| Match: | 1olzA |
| Description: | The ligand-binding face of the semaphorins revealed by the high resolution crystal structure of SEMA4D |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [109-484] |
1 11 21 31 41 51
| | | | | |
1 CSPRSNCQDD ANDPLYWVSY KTGKCTTITS VVPHQLQRTT ARTLELIIDH LPQLKENLIC 60
61 AFTTEDKALF TNATKKRNGV NCTTPRTDML PQIEQGKHHF TAKLSVRTRN GPDLVSTDFT 120
121 FFDCSTHSSC TRCVSSEFPC DWCVEAHRCT HDTAENCRND ILVTGVSRIG PSYRSGPGFC 180
181 PTINATGDGS EVLVAGGTSK SIKVKVHIIG QFIVQTRFVC QFNIEGRVTS LNAQLLGDTI 240
241 YCDSMEFQYT SRSPNLTATF AVIWGGSKPL DNPHNIHVVI YRCREMADSC GICLALSEKY 300
301 NCGWCSSTNT CEVEEQCNKN KEGKTDWLNR SEICPNPEIH TFQPKTGPWE GGTNITIRGI 360
361 NLGKNYNDIY SGVRIA
|
| Detection Method: | |
| Confidence: | 11.39794 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein binding | 2.30744405151563 | bayes_pls_golite062009 |
| receptor binding | 1.70177010329948 | bayes_pls_golite062009 |
| binding | 1.63967303762968 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.18463863965142 | bayes_pls_golite062009 |
| growth factor activity | 0.59278308192712 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 0.437338899624441 | bayes_pls_golite062009 |
|
Region A: Residues: [485-635] |
1 11 21 31 41 51
| | | | | |
1 GINCMPFPQF YIDTKQIVCT VDSPGEQMYR NGKIVVQIGD YRGESKEDYE FVDPKILDFN 60
61 PKFGPTSGGT EIHITGKHLN AGSRIQASIN DHLPCKILST DSSQAICRTS ASPGIIEGRL 120
121 KMSFDNGPRE FNDYNFKYVL DPTVEHVSSG P
|
| Detection Method: | |
| Confidence: | 24.39794 |
| Match: | 2uzxB |
| Description: | No description for 2uzxB was found. |
|
Region A: Residues: [636-865] |
1 11 21 31 41 51
| | | | | |
1 SGQIKVPKGI PAGGIRISVT GTQFTSIQNP NIYVVYNGEM YASPCRVQSD TEMECASPVV 60
61 DVDSHVIEAE RPILLEYGFL MDNVLRVQNL SKVHNNHFEL YPNPEYFIFE ERVKYFKSEY 120
121 LTINGRNLDR ACKESDVEVK IGNGFCNITS LSRQQLTCRP PSEATATKSM NGPEVIVRIG 180
181 TSLEYRIGIL SYESSNIILD WGENVIFAVI ATIVILLLIF VALLVAYKKK
|
| Detection Method: | |
| Confidence: | 2.18 |
| Match: | 2uzxB |
| Description: | No description for 2uzxB was found. |
|
Region A: Residues: [866-928] |
1 11 21 31 41 51
| | | | | |
1 SSESSRVLRN MQEQMDILEL RVAAECKEAF AELQTEMTDL TGDLTSGGIP FLDYRSYAMK 60
61 ILF
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [929-1039] |
1 11 21 31 41 51
| | | | | |
1 PNHEDHIVLQ WERPELLRKE KGLRIFGQLI MNKTFLLLFI RTLESNRYFS MRERVNVASL 60
61 IMVTLQSKLE YCTDILKTLL GDLIEKCIEG KSHPKLLLRR TESVAEKMLS A
|
| Detection Method: | |
| Confidence: | 10.221849 |
| Match: | 1r0pA |
| Description: | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met in complex with the microbial alkaloid K-252a |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1040-1236] |
1 11 21 31 41 51
| | | | | |
1 WFTFLLYKFL KECAGEPLYM LFRAVKGQVD KGPVDACTHE ARYSLSEEKL IRQSIDFRPM 60
61 NVYASIIQQP IFCNNLDMLP SHTENVSVKV LDCDTIGQVK EKCLETIYRN IPSSQRPRKD 120
121 DLDLEWRTGA TGRVILYDED VTSKTESEWK KLNTLQHYNV PDGAGLSLVP KQSSIYNFSI 180
181 LSDKNEKSHK YETLNIS
|
| Detection Method: | |
| Confidence: | 41.39794 |
| Match: | 2r2oA |
| Description: | No description for 2r2oA was found. |
|
Region A: Residues: [1237-1505] |
1 11 21 31 41 51
| | | | | |
1 KYTSSSPTFS RAGSPLNNDM HENGLRYWHL VKHHDSDMQK EGERVNKLVS EIYLTRLLAT 60
61 KGTLQKFVDD LFETIFSTAH RGSALPLAIK YMFDFLDDQA QLHGITDPEV VHTWKSNSLP 120
121 LRFWVNLIKN PNFVFDIHKS NIVDSCLSVV AQTFMDSCST SDHRLGKDSP SSKLLYAKDI 180
181 PEYRKWVDRY YRDIRDMSPI SDQDMNAMLA EESRLHTTEF NTNCALHELY TYAVKYNEQL 240
241 TVTLEEDEFS QKQRLAFKLE QVHNIMSSE
|
| Detection Method: | |
| Confidence: | 1.49 |
| Match: | 1nf1A |
| Description: | GAP related domain of neurofibromin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein binding | 1.47356170396493 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.39082200655299 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.32712330053994 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.32332610568436 | bayes_pls_golite062009 |
| GTPase activator activity | 1.26194925603349 | bayes_pls_golite062009 |
| enzyme activator activity | 1.25756739840692 | bayes_pls_golite062009 |
| binding | 0.90203495506529 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.889119908410775 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 0.811555335811836 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 0.539480685576633 | bayes_pls_golite062009 |
