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View Structure Prediction Details

Protein: MED26-PA, MED26-PB
Organism: Drosophila melanogaster
Length: 1483 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED26-PA, MED26-PB.

Description E-value Query
Range
Subject
Range
gi|28317037 - gi|28317037|gb|AAO39538.1| RE09558p [Drosophila melanogaster]
1374.0 [0..310] [1483..1]

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Predicted Domain #1
Region A:
Residues: [1-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQIEIQELT THLSQALDQN YDVVNMDAVL CVICALEGTT ITKEQLEATR LAKYINQLRR  60
   61 RTKNEHLARR AKSLLKKWRE MVGIQQTATE NLAHPSQISS SQPALDLVKS PITSFITEPI 120
  121 APSQQIVSDL HSNIDSAEPP LSGEHTLLHP NFSNLVNSIK DSDRHENIAI TTLHTHKDRR 180
  181 HSHSIRSCHV ASPQPIVIDH SVNSVINLTD DSTVKINEAS VVIDIASDSD ENDNNGSLNP 240
  241 KKLNSIVPAP LPIPSTPSSR QRKLKKEKRS KEREGQVATN TRFGAKASDG FQQAALTTDS 300
  301 EIFSLSNSSM SSIVSGDATS SYSQNKSRLN SNELTFTGRF KAVDHLFRST ESGKHKIDEY 360
  361 SA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.30103
Match: 1pqvS
Description: RNA polymerase II-TFIIS complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [363-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDSNASCSRL SPSTVDEVKK AEHLFDAQLT NTTANQIPMS AVSIGYESNT RHEYLESDSP  60
   61 SQIPKRRGRK KGSKGVDALI AKESSSLSQQ IFFGGSTVKK VKTTKELFNE IQSRKLSVSM 120
  121 QSSASNLSNS STNRDLPSHT TFPRQTSSCS DTSMNSPHIL ETLSGSAIFA SKIDDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [539-777]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNTDSDTVTS DPSHDSNKSQ EIKECTSLDS NSNSIQSLPL ANNRENLIPT NVNDITTQLM  60
   61 HLIHSLNSPL SEIEIERVYQ EKIIPCTCIV IEGVQGTLGE SNNSTLDEQS YNAKISLNSK 120
  121 DNLSCHNQDN YSTSQRSVNG EVIDTQPKLV KSIFDLDFDD NDDPLYFIMD EIQKPIARAD 180
  181 ELKNNKSDTK NINFGASAQN ASLNIIHFND DAQQDNSNQE RGKNETQNAI PAFTVHEDP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [778-1008]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCLARQRFYI QTNKVTSFHI NALHNYYIPN INGNWDSVES FTSFQSEHTI MDTMESYTVT  60
   61 NGADVVPKYG LLTSDRIRKD LSSLKSIKPY RVKNFTSLIS PFLGVAKCLP TCRRARRRFK 120
  121 NFVNSSTAND KISNNFESLE NMKTSFKNCN PLNVKIDGTT SAIYSHNENH VPMQVNTNVE 180
  181 QLPPSQSFSS NAISYNLLKL ADDKVCHDGI SDKSSNTGCQ GNSPYSSSSS S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1009-1141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYSGRKEDQH IITKNLQNKN IQLNSRKSDM KRRKRIYLEN DSKKKKHYRK RIKTAVNRTF  60
   61 SNLHRNLYSI DSENGMKNDY KNEYGNSNNE EYAIVQRPAG DGENCSNHIV LTIKKTPSKI 120
  121 NSPANSMTAF SPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1142-1370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSDGANLQK SILDLRLEDT NISQSITEIP QKKDLSKTDR IVHQSRSSAY RRIFRKPDKS  60
   61 QTKFIDLDLK HLFHLKANSP CISANAKLHN KLFFPHELSR DNTSGIRERL INYSSSSSSS 120
  121 YDDDSEVENT SFLKKANVNK FSASNNRNLK TETETCAATA ISEFKFESDE DSILTSLGDS 180
  181 DIDIQDEIQV INDKVDYCND FQNNKMLESF NSIFVDSLRT NTKNASDNM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1371-1483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSSAHITSLE SLKPENADAI TRYCNNNNLG VNLSNELSNI SAKPLKSFDS TMKLPSLGIE  60
   61 HCTGIKTSSD MASTNIAEKK LTRIQQFKEW HQVLQLRSYN NEPLIVLPYV LLE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle