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View Structure Prediction Details

Protein: FBpp0311396, Thd...
Organism: Drosophila melanogaster
Length: 1738 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311396, Thd....

Description E-value Query
Range
Subject
Range
gi|4928444 - gi|4928444|gb|AAD33588.1|AF132141_1 G/T mismatch-specific thymine DNA glycosylase [Drosophila melano...
704.0 [0..644] [1738..1]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEESGSTPL LSSSFSYTPT VAPLVLKIAL IQAARSFAAS KYTIKVLLSL NLALSEQAIV  60
   61 QKAVKPICTV MASEVDASSG PEDGTVPTLM SLTPYITNLE HGNNESGKYV SGLPNNRKRQ 120
  121 KLSILEHNTI QN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [133-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDVDNTEVEP NMDPKSKMSD TKSNKYSEME KHLNDNSKIV IEGTISIGNS KRKSPEKLVP  60
   61 YDNDCYMPPE QALVTSVELV VPAPQTHSSN TPGRQSEEPN LSTLGESSTT PSSTIDNKLQ 120
  121 YSTAGLYNST SSTSILANDK IVGCANDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [281-535]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNLNLRIPTK LVVTTASGDI LIDDRRASLW TPHHDESGQR QQRTGTASSD TKQEPMNVSS  60
   61 ELSYHHQNRH SELLLQIEKE SSGSFLQASP IPLQDNHNNA ASGQFGQTEE TSNIDSQSHN 120
  121 NFYAQMMQPQ HLLHNQHQQS MHEHSPRHQQ PASYSGYITH YQNPPMFGAH QSEHHQRLNQ 180
  181 QQQPLQHLLD CHGHLEQSTP ISQQNQHHLS QQIHQHQHQQ THQRLPLREN YHDIIMDDFH 240
  241 EEPSHAFKLT LSPSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [536-775]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKPENQDDGY ETSAGDVLTP NSHSSSTHSI TPQHQMQHSN IVLMTQNQKK SDDLQLTKVT  60
   61 LSGEAHTDPN ACSSNSSQGQ VLASQSHLEL SEGTRCSSHA SVVDPYSFMG EELHMHSPSH 120
  121 RHLDAVTTGP GRYGILVSND TPECLSREMY RHSQQSTTVL EQTDSSSCGI NFKPMPKKRG 180
  181 RKKKLVAVNA DTSQMTTPVD QQKVSAGRAD CEDGGGDQAA KPKERKKHDR FNGMSEEEVI 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [776-1045]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRTIPDHLCD NLDIVIVGIN PGLFAAYKGH HYAGPGNHFW KCLYLAGLTQ EQMSADEDHK  60
   61 LIKQGIGFTN MVARATKGSA DLTRKEIKEG SRILLEKLQR FRPKVAVFNG KLIFEVFSGK 120
  121 KEFHFGRQPD RVDGTDTFIW VMPSSSARCA QLPRAADKVP FYAALKKFRD FLNGQIPHID 180
  181 ESECVFTDQR IRLCSAQQQV DIVGKINKTH QPPLGDHPSS LTVVSNCSGP IAGDAECGIV 240
  241 AEESDQVQSE KMIPQMDPTV PSSSNATDGK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.69897
Match: 1wywA
Description: Crystal Structure of SUMO1-conjugated thymine DNA glycosylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA N-glycosylase activity 4.49770781621045 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 4.14479139843076 bayes_pls_golite062009
uracil DNA N-glycosylase activity 3.90350764950421 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 2.96262005834299 bayes_pls_golite062009
catalytic activity 1.96155289609929 bayes_pls_golite062009
hydrolase activity 1.80710505371922 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [1046-1228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFSYTAENTP LLPVSNHNPS INENNYLSVM GSQQPLSQQP LEKKKRGRPK KIKGQDIIDH  60
   61 SVGGKASIAG QHIPSHDFNN ILNLSVMSGG GTIETPKKKR GRPKKLKPAI DNIMTVKQLQ 120
  121 HGNNNLNTTA GLSASSMHPI SMEHIAASPQ SSHQMPPSLY NTPPPSHLLY TASASPMASP 180
  181 ALN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1229-1294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CNYTQVHGHG TPPVGQVASV AQGSSPVIDT QNDHLAQQKQ SHHGNLGAGL DMRDHPHLGE  60
   61 TPPPSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1295-1482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNMCSTVDFD PPDEHSGSQV GSRVQNKAVE LDHQHPQIME KVQYDSPVPN TEANPAHPHE  60
   61 NYQQWLSPHP HQSNQPAQKL THRQQHPPMH HFHQEQTENW QRYEEQNSNP YMVISAHHQH 120
  121 LSPRLGNQTH QNSSPSGHIS SDVAHKSLCG LESLVDQIPA IREQDCSNIP LATVAAAAAA 180
  181 VESRILSL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1483-1738]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHQHQHPLQP HQQNQQNQQQ QLKQCKQENS AHRESCRPTS ENSNVSNSNF SVSSLAASAS  60
   61 SARTDNAIYG NGETKGNNES SHHNSCDTNI DYPIHNQSAY HHTPHLIGSA LGTNVNNSEP 120
  121 NLHTISHPHP PHPHPHSMYV DQAHHMAHIP SVNVNSMYGP AYGSHPQHTT GEYPGTHGHY 180
  181 SLGGSVQTAV PTSSATLHVP SPNYPFGHHP YGHTPPQANY PSYTHPHTHH HHSHPSHHLT 240
  241 VFDHLKPSDI SGYGGF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.95
Match: 2jrnA
Description: No description for 2jrnA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle