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View Structure Prediction Details

Protein: wts-PA
Organism: Drosophila melanogaster
Length: 1105 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wts-PA.

Description E-value Query
Range
Subject
Range
gi|903942 - gi|903942|gb|AAA70336.1| LATS
443.0 [0..1] [1105..1]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHPAGEKRGG RPNDKYTAEA LESIKQDLTR FEVQNNHRNN QNYTPLRYTA TNGRNDALTP  60
   61 DYHHAKQPME PPPSASPAPD VVIPPPPAIV GQPGAGSISV SGVGVGVVGV ANGRVPKMMT 120
  121 ALMPNKLIRK PSIERDTASS HY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [143-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRCSPALDSG AGSSRSDSPH SHHTHQPSSR TVGNPGGNGG FSPSPSGFSE VAPPAPPPRN  60
   61 PTACSAATPP PPVPPTSQAY VKRRSPALNN RPPAIAPPTQ RGNSPVITQN GLKNPQQQLT 120
  121 QQLKSLNLYP GGGSGAVVEP PPPYLIQGGA GGAAPPPPPP SYTASMQSRQ SPTQSQQSDY 180
  181 RKSPSSGIYS ATSAG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [338-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSPITVSLP PAPLAKPQPR VYQARSQQPI IMQSVKSTQV QKPVLQTAVA PQSPSSASAS  60
   61 NSPVHVLAAP PSYPQKSAAV VQQQQQAAAA AHQQQHQHQQ SKPPTPTTPP LVGLNSKPNC 120
  121 LEPPSYAKSM QAKAATVVQQ QQQQQQQQQQ VQQQQVQQQQ QQQQQQLQAL RVLQAQAQRE 180
  181 RDQRERDQRE RERDQQKLAN GNPGRQMLPP PPYQSNNNNN SEIKPPSCNN NN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [570-631]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQISNSNLAT TPPIPPAKYN NNSSNTGANS SGGSNGSTGT TASSSTSCKK IKHASPIPER  60
   61 KK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [632-1105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISKEKEEERK EFRIRQYSPQ AFKFFMEQHI ENVIKSYRQR TYRKNQLEKE MHKVGLPDQT  60
   61 QIEMRKMLNQ KESNYIRLKR AKMDKSMFVK LKPIGVGAFG EVTLVSKIDT SNHLYAMKTL 120
  121 RKADVLKRNQ VAHVKAERDI LAEADNNWVV KLYYSFQDKD NLYFVMDYIP GGDLMSLLIK 180
  181 LGIFEEELAR FYIAEVTCAV DSVHKMGFIH RDIKPDNILI DRDGHIKLTD FGLCTGFRWT 240
  241 HNSKYYQENG NHSRQDSMEP WEEYSENGPK PTVLERRRMR DHQRVLAHSL VGTPNYIAPE 300
  301 VLERSGYTQL CDYWSVGVIL YEMLVGQPPF LANSPLETQQ KVINWEKTLH IPPQAELSRE 360
  361 ATDLIRRLCA SADKRLGKSV DEVKSHDFFK GIDFADMRKQ KAPYIPEIKH PTDTSNFDPV 420
  421 DPEKLRSNDS TMSSGDDVDQ NDRTFHGFFE FTFRRFFDDK QPPDMTDDQA PVYV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.522879
Match: 2esmA
Description: Crystal Structure of ROCK 1 bound to fasudil
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle