






| Protein: | Axn-PA, Axn-PB |
| Organism: | Drosophila melanogaster |
| Length: | 745 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Axn-PA, Axn-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
596.0 | [0..1] | [745..1] |
|
Region A: Residues: [1-184] |
1 11 21 31 41 51
| | | | | |
1 MSGHPSGIRK HDDNECSGPR PPVPGEESRV KKMTEGVADT SKNSSPSYLN WARTLNHLLE 60
61 DRDGVELFKK YVEEEAPAYN DHLNFYFACE GLKQQTDPEK IKQIIGAIYR FLRKSQLSIS 120
121 DDLRAQIKAI KTNPEIPLSP HIFDPMQRHV EVTIRDNIYP TFLCSEMYIL YIQQMSAQQE 180
181 RCTS
|
| Detection Method: | |
| Confidence: | 45.221849 |
| Match: | 1agrE |
| Description: | Regulator of G-protein signalling 4, RGS4 |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| GTPase regulator activity | 1.92987277493861 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.90800479999702 | bayes_pls_golite062009 |
| GTPase activator activity | 1.87534424848905 | bayes_pls_golite062009 |
| beta-catenin binding | 1.80347214616493 | bayes_pls_golite062009 |
| binding | 1.71250041369331 | bayes_pls_golite062009 |
| enzyme activator activity | 1.62073651679221 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.49796137854909 | bayes_pls_golite062009 |
| protein binding | 1.34804002381061 | bayes_pls_golite062009 |
| armadillo repeat domain binding | 0.461171601616737 | bayes_pls_golite062009 |
|
Region A: Residues: [185-277] |
1 11 21 31 41 51
| | | | | |
1 SGATGSGSAG SSGSGGSSLA GACALPPTTA SGKQQLPQLV PPGAFINLPV SSVSGPPAGT 60
61 CSASGSVYGP STSASSSGSI SATDTLPRSS TLP
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [278-468] |
1 11 21 31 41 51
| | | | | |
1 TLHEDSVLSL CDDFEKVQMQ EGGGSLGSGS VGAGARAPDY PIRLTRDLLI ATQKRRLEIR 60
61 PPGAHGYVYN PSTTNTSYVP NSRVDSERAS VSSGGRTDSD TMSISSCSMD GRPYIQRRHS 120
121 STESKAIRQS AMANKETNTF QVIPRTQRLH SNEHRPLKEE ELVSLLIPKL EEVKRKRDLE 180
181 ERARERNPGA A
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [469-664] |
1 11 21 31 41 51
| | | | | |
1 LLTNERSSAS DRAFAEAIRE KFALDEDNDQ DILDQHVSRV WKDQTPHRSP GTMSPCPPIP 60
61 SRRRTATHDS GMVSDGAMSL SGHSMKHSKS MPDHSSCSRK LTNKWPSMNT DSGISMFSAD 120
121 TVTKYKDASS RSGSSTASKL EEAKRRLEDE PRRSRRYAQP PMQHLSQQPL ASFSSSSSGG 180
181 SISLPHQPPP LPAKPP
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [665-745] |
1 11 21 31 41 51
| | | | | |
1 ETIVVFSFCE EPVPYRIKIP GTQPTLRQFK DYLPRRGHFR FFFKTHCEDP DSPVIQEEIV 60
61 NDSDILPLFG DKAMGLVKPS D
|
| Detection Method: | |
| Confidence: | 36.221849 |
| Match: | 1wspA |
| Description: | Crystal structure of axin dix domain |
Matching Structure (courtesy of the PDB):![]() |
|