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View Structure Prediction Details

Protein: CG11837-PA
Organism: Drosophila melanogaster
Length: 306 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11837-PA.

Description E-value Query
Range
Subject
Range
gi|108884724, gi... - gi|157126646|ref|XP_001654689.1| dimethyladenosine transferase [Aedes aegypti], gi|157103251|ref|XP_...
274.0 [0..1] [306..1]

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Predicted Domain #1
Region A:
Residues: [1-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKVTKEKKS RIHNDVQKQG IVFNKDFGQH ILKNPLVITT MLEKAALRAT DVVLEIGPGT  60
   61 GNMTVRMLER AKKVIACEID TRLAAELQKR VQATPLQPKL QVLIGDFLKA ELPFFDLCIA 120
  121 NVPYQISSPL IFKLLLHRPL FRCAVLMFQR EFAERLVAKP GDKLYCRLSI NTQLLARVDM 180
  181 LMKVGKNNFR PPPKVESSVV RLEPKNPPPP VNFTEWDGLT RIAFLRKNKT LAATFKVTSV 240
  241 LEMLEKNYKL YRSLRNEPIE DDFKMQDKVI SILEEQDMAA KRARSMDIDD FMRLLLAFNS 300
  301 AGIHFN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.39794
Match: 1zq9A
Description: Crystal structure of human Dimethyladenosine transferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
rRNA methyltransferase activity 4.09362182773099 bayes_pls_golite062009
N-methyltransferase activity 4.00768472859991 bayes_pls_golite062009
methyltransferase activity 3.57681394097837 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.49392219433935 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
transferase activity 2.22303238506686 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 2.00108769169811 bayes_pls_golite062009
RNA binding 1.99752836873461 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 1.83964463328968 bayes_pls_golite062009
tRNA methyltransferase activity 1.76571145896453 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 1.75675289134467 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
protein methyltransferase activity 0.94499223839747 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
rRNA (uridine-2'-O-)-methyltransferase activity 0.90544396691236 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
binding 0.777596419415505 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.742142092552002 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
mRNA binding 0.0540207721800283 bayes_pls_golite062009
histone methyltransferase activity 0.0408000230099101 bayes_pls_golite062009
snoRNA binding 0.00848192089639488 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle