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View Structure Prediction Details

Protein: WASp-PC
Organism: Drosophila melanogaster
Length: 494 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WASp-PC.

Description E-value Query
Range
Subject
Range
WASp-PB, WASp-PA... - The gene WASp is referred to in FlyBase by the symbol Dmel\WASp (CG1520, FBgn0024273). It is a prote...
gi|220957180, gi... - gi|220957180|gb|ACL91133.1| WASp-PA [synthetic construct], gi|220947946|gb|ACL86516.1| WASp-PA [synt...
252.0 [0..3] [494..36]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRKLKTLNT AVVQIYKTEG SAHAHWKKRH TGVVCFVKDS AIRSYFMRAY CLIKNELIWE  60
   61 HEIYDGMEVV KSRPFLLTFE GSDGHVGLNF VSEEECDSFF RIVDATI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.0
Match: 2ifsA
Description: No description for 2ifsA was found.

Predicted Domain #2
Region A:
Residues: [108-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETRNRKRQEK RNRQKSQQAP NAPLPQVQRE PARPPPMQGG LSSTDGVQLR NNKINSVTLT  60
   61 PAPAPAQSKN FLSSSF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [184-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLGNNAKDKK RKVTKADISR PTNFVHLSHV GWDAQKGFDL AGNENDEVLN EFFVKAGVSE  60
   61 VELKDRDTRA FIYDFIQSNN VLASVKQYSV ESPTETAAPM PPPVPTRHPS NGNQRTAPPL 120
  121 PPARQPPPAV PVTVPGAARA PPPPNRPPPI STAPPPPPVS APVVAPPPPP PPPPAAVPPP 180
  181 PPPPMPV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.03
Match: 1ej5A
Description: Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [371-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEIPVITTTH APTQAARPAA PAAPDPRNAL MDAIRKGTQL KKVDTTALST GSGDSRSDLM  60
   61 KDIRQGTVLK PAKERELGSQ RNSDSGAGTD ALADALRRAL AARGNAIHSD EDETESSDNE 120
  121 GEWD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle