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View Structure Prediction Details

Protein: gi|7301561, gi|4...
Organism: Drosophila melanogaster
Length: 653 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7301561, gi|4....

Description E-value Query
Range
Subject
Range
gi|254200, gi|75... - pir||S40962 DNA polymerase alpha primase - fruit fly (Drosophila melanogaster), gi|254200|gb|AAB229...
578.0 [0..1] [653..1]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIDKKTQAG VKSIIGWQHC AHFYRQNKLL GLFTKIKRPT KGQRMEEELK QQFDEMGVEP  60
   61 ADAVLGRCAE LAITYNIHDA TEFVEQWMAF SLSHLQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEDPAIENLG DFERKVLQLR KDKAGYKATG QKAKSYGSPS VQDTSSLATY GVMEDDPMLD  60
   61 DYVSESAVDS SALHTPKAKK QSDRTANLKG AALFSPASYT PQSAKRKAGL ETPSNSVAGK 120
  121 PGDIVDTFGH PKLLAGSSWQ 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [237-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQMEHTVPVT QKLLHNDAPL TIANLGYMND LLTDRCHNLR VRFNQTGPAL VDKKLGQAGA  60
   61 AECIWYPQDR QVLQSAGGLH AVGMIHSEDD GPLDAHSAFM AVLDDDVEDE MDPTLTLNFS 120
  121 RVKSASIFPG QVVLAKGFIP RGKTFMVEEI HTERKLTPAT PLQIDR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [403-653]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELQFVVASGP FTDSTDLFYE PLHDLLKYLK DHRPDVLVLT GPFLDADHKM VGELAETFDT  60
   61 FFEKMIGGIM ESIGSHTAVL VVTSQKDAMA LSVYPTPPPA LRRTYPNLYM LPDPSLVDLD 120
  121 GFTLGVTSTD VVDHLLSHEF AVNAGERMHR AINHLFHQGS FYPLYPPADE DMAYDSQLAL 180
  181 KYAQLKQLPN VLILPSDQRH FIRLVNDCLV INPGRVADKK GGTFARFLVA PSVPGKAANM 240
  241 FNSVACQVQR I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1ii7A
Description: Mre11
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.15398287574737 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.11518948144723 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.72108778738758 bayes_pls_golite062009
catalytic activity 1.39852585255405 bayes_pls_golite062009
phosphoprotein phosphatase activity 1.23036240099336 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.899406797746366 bayes_pls_golite062009
binding 0.852545739165539 bayes_pls_golite062009
phosphatase activity 0.76188635342041 bayes_pls_golite062009
transporter activity 0.72444760979153 bayes_pls_golite062009
protein binding 0.682314750442084 bayes_pls_golite062009
structural molecule activity 0.204234628453541 bayes_pls_golite062009
substrate-specific transporter activity 0.169394141800139 bayes_pls_golite062009
protein transporter activity 0.10469955758282 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle