YRC Public Data Repository - Protein Structure Prediction

Protein:	HLHm7-PA
Organism:	Drosophila melanogaster
Length:	186 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HLHm7-PA.

Description	E-value	Query Range	Subject Range
gi\|55715451 - gi\|55715451\|gb\|AAV59242.1\| enhancer of split complex m7 protein [Drosophila simulans]	132.0	[0..1]	[186..1]
gi\|55715016, gi\|... - gi\|55715016\|gb\|AAV59028.1\| enhancer of split m7 protein [Drosophila yakuba], gi\|195504131\|ref\|XP_002...	129.0	[0..1]	[186..1]
gi\|55715373, gi\|... - gi\|55715373\|gb\|AAV59170.1\| enhancer of split complex m7 protein [Drosophila melanogaster], gi\|557152...	125.0	[0..1]	[186..1]
gi\|1017761 - gi\|1017761\|gb\|AAA79185.1\| hairy1	119.0	[0..2]	[161..23]
gi\|47225756 - gi\|47225756\|emb\|CAG08099.1\| unnamed protein product [Tetraodon nigroviridis]	115.0	[0..3]	[178..24]
gi\|37590864, gi\|... - gi\|37590864\|gb\|AAH59551.1\| Her6 protein [Danio rerio], gi\|169158177\|emb\|CAQ13541.1\| hairy-related 6 ...	115.0	[0..3]	[172..24]
gi\|125776134, gi... - gi\|54638920\|gb\|EAL28322.1\| GA13073 [Drosophila pseudoobscura pseudoobscura], gi\|125776134\|ref\|XP_001... gi\|194111963, gi... - gi\|195151959\|ref\|XP_002016906.1\| GL22021 [Drosophila persimilis], gi\|194111963\|gb\|EDW34006.1\| GL2202... gi\|54638920\|gb\|E... - GA13073-PA [Drosophila pseudoobscura], GA13073 [Drosophila pseudoobscura pseudoobscura]	114.0	[0..1]	[186..1]

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Predicted Domain #1

Region A:
Residues: [1-121]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKYEMSKT YQYRKVMKPL LERKRRARIN KCLDELKDLM AECVAQTGDA KFEKADILEV  60
   61 TVQHLRKLKE SKKHVPANPE QSFRAGYIRA ANEVSRALAS LPRVDVAFGT TLMTHLGMRL 120
  121 N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.39794
Match:	1nkpA
Description:	Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [122-186]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLEQPMEQPQ AVNTPLSIVC GSSSSSSTYS SASSCSSISP VSSGYASDNE SLLQISSPGQ  60
   61 VWRPW

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.611	a.4.1	Homeodomain-like
View	Download	0.579	a.4.1	Homeodomain-like
View	Download	0.443	a.4.1	Homeodomain-like
View	Download	0.422	a.144.1	PABC (PABP) domain
View	Download	0.378	a.144.1	PABC (PABP) domain
View	Download	0.360	a.159.2	FF domain
View	Download	0.360	d.52.10	Description not found.
View	Download	0.316	a.4.1	Homeodomain-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits