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View Structure Prediction Details

Protein: gi|23172248, gi|...
Organism: Drosophila melanogaster
Length: 244 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|23172248, gi|....

Description E-value Query
Range
Subject
Range
gi|46409142 - gi|46409142|gb|AAS93728.1| RE51991p [Drosophila melanogaster]
193.0 [0..1] [244..1]

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Predicted Domain #1
Region A:
Residues: [1-63]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADNAEPLTL SRDVKRSIEL LEKLQASGDF PTTKLAALQK VLNSDFMTSV REVYEHVYET  60
   61 VDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.30103
Match: 1y74A
Description: Solution Structure of mLin-2/mLin-7 L27 Domain Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
epidermal growth factor receptor binding 3.177198454733 bayes_pls_golite062009
PDZ domain binding 1.88298566187849 bayes_pls_golite062009
binding 1.7694276265893 bayes_pls_golite062009
protein binding 1.15557714383339 bayes_pls_golite062009
receptor binding 0.740295502613934 bayes_pls_golite062009
protein domain specific binding 0.683298345987 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [64-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGSHDVRASA TAKATVAAFA ASEGHAHPRV VELPKTEEGK TRPYELRIEG IPLYHKTNTL  60
   61 IVKVYRPRIY VSIIHLI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [141-244]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKALSIFNFC FSGLGFNVMG GKEQNSPIYI SRIIPGGVAD RHGGLKRGDQ LLSVNGVVRE  60
   61 NHEKAVELLK QAVGSVKLVV RYTPKVLEEM EMRFDKQRNT RRRQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 2dkrA
Description: No description for 2dkrA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle