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View Structure Prediction Details

Protein: CG5720-PA
Organism: Drosophila melanogaster
Length: 1004 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5720-PA.

Description E-value Query
Range
Subject
Range
gi|70878483 - gi|70878483|gb|EAN91735.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71649745 - gi|71649745|ref|XP_813586.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
356.0 [0..24] [969..688]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MECNLGSEIG QKMRSAVKAK LLELGTGGSA GFIDDELPDY VMVMVANKRT KQQMNAELNL  60
   61 FLGDQTDLFV TWLHEVLQKL QEVTLPTSSA 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.14
Match: 1miuA
Description: BRCA2 helical domain; BRCA2 tower domain; OB-fold domains of BRCA2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [91-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKKRKSRGQ EKDKKGSKKD KRPHRKSGDE LSEPQPSSSD AMPIVSSITD VFAEELLEKA  60
   61 KKTMDIDLSA KDEILHKKKN RKSIEDEDAS ANRALDVPAV SEIISTTIGV NRQKDLAELA 120
  121 EIQKKIHAAK KHLRQIGEIG DESDEYDEDL LNLSAREESV DQEPEEDPPK LEAPPRKAKS 180
  181 PIIFNRREKT PEKRPEAEPE IDSRQEEAEE KSPKKDSSAD KAKEDRSERR SVHDRLGSKA 240
  241 QTPADRSQRN QKELYVPTHR RRSEPEATKE RSQRERTRER RSSRDTSRDT NRNQRQRRSP 300
  301 SPEAPSTKQR IVSQVIVAVN KPPEPSDDED MAEKPVNSVI KVKPRPNVSP RRQACKNLLL 360
  361 RAVADAQRST ILAKTSTQKE DEDVGKIISS LGKRKSEDKN DQIRKRNRER KRRKRSAQGN 420
  421 ELFRRTTREL VVNVTQRDGK RERRSNERRA EIKVVEEEYT PSLMTEGVET YVPQLLTNVD 480
  481 ELDLHISSHD EPSPNSGALK TQFVVTLNGD KA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.988
Match: 1yvlA
Description: Structure of Unphosphorylated STAT1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [603-815]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGGKNVKGGA SRKRPSNSRK RSTSPVSTPQ VSSSNIEPTS TTVDKRRRSN RDRSFSPSPR  60
   61 QSSGSPSLPT TRSINRNEVR RQPQEIKKII IKNDTDEDDE MHGSPKKRSP NKRQPAAANG 120
  121 HKDNKDKGKI EEGSTTPPLP AKPKARAEKK ASSKEKSVRS NSAETSSAAK SVSASTSVST 180
  181 TTKAKHTPIR FTLKSEDEPS ASKKRRSGSP DRD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [816-1004]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAAPERRRVS IRNPEDRKYD NLPALSAVSV DSTVLKVNKP KERCKYHPNC TKQFCEYYHP  60
   61 TAPCKSFPNC KFADKCMYSH PKCKFDMACM SIDCNYAHGG QRDLSHVQLA APPLSSHVIP 120
  121 VQNYKSISAP VTSTTATTMC KYYPNCSKLG CTFYHPKPCR FGKNCVNKLE CIFYHPEMQS 180
  181 KFKWVASLG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.48
Match: 1nbsA
Description: Crystal structure of the specificity domain of Ribonuclease P RNA
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle