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View Structure Prediction Details

Protein: Orct-PA, FBpp0306893
Organism: Drosophila melanogaster
Length: 548 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Orct-PA, FBpp0306893.

Description E-value Query
Range
Subject
Range
gi|1934852 - gi|1934852|emb|CAA73031.1| putative organic cation transporter [Drosophila melanogaster]
357.0 [0..1] [548..1]

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Predicted Domain #1
Region A:
Residues: [1-548]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYDDVITHL GEFGPYQKRI YYLLCLPAIV CAFHKLAGVF LLAKPDFRCA LPYENGSIYE  60
   61 LSPHLWNLSY PENERCSYYD VDYTEEYLNG SIPRSSNETK TCSSYVYDRS KYLNSAVTEW 120
  121 NLVCSRSLLS ATSDSLFMLG VLLGSLIFGQ MSDKLGRKPT FFASLVLQLI FGVLAAVAPE 180
  181 YFSYTISRMI VGATTSGVFL VAYVIALEMV GSSYRLFAGV AMQMFFSVGF MLTAGFAYFI 240
  241 HDWRWLQIAI TLPGLLFLCY YWIIPESARW LLMKGRKDEA FVIIEKAAKE NKVEVPNEIY 300
  301 EQLVDEVAEK KKQDEMAASQ PAATVFDLLR YPNLRRKTLL IFFDWFVNSG VYYGLSWNTN 360
  361 NLGGNQLVNF MISGAVEIPG YTLLLFTLNR WGRRSILCGT MMVAGISLLA TIFVPSDMNW 420
  421 LIVACAMIGK LAITSSYGTI YIFSAEQFPT VVRNVGLGAS SMVARVGGIL APYLKLLGEI 480
  481 WRPLPLIICG ALSLTAGLLS LLLPETLNKP MPETIEDGEN FGKKPAPQET AEEGGTQELS 540
  541 GMLNGKSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.94605227012838 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
organic anion transmembrane transporter activity 3.3413526350788 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.52916479889426 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 2.39244854801368 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 2.39244854801368 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.15783210522667 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.46605775041083 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
phosphate transmembrane transporter activity 0.312628600969375 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

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