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View Structure Prediction Details

Protein: CG5524-PA
Organism: Drosophila melanogaster
Length: 1122 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5524-PA.

Description E-value Query
Range
Subject
Range
gi|73980575 - gi|73980575|ref|XP_532882.2| PREDICTED: similar to SMC6 protein [Canis familiaris]
321.0 [0..15] [1122..483]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERSRRGRIR RMPSPGSESD GSTAEPTRKR SKQQFVAEAE PDFVEEETEK YANASTSQTA  60
   61 RSRNKQARQT TLNMSQRSVN FNLTSELSIP NAFDRC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKVISMRLTN FMCHSNLFIE FGPNINFLVG NNGSGKSAVI TALALGLTSS ARATNRASSI  60
   61 QKLIKNGEVS ATISITLSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.154902
Match: 1w1wA
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [176-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGLRPFKADI FGPHLTVVRQ IRHSSSTYDL QDARGKSVSK KVSDIRRMLL CFGINVENPI  60
   61 FVLNQEAARE FLKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [250-604]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEPASNYKLL MKATQLDVCT SSLTECHALR RHFTQELEQL EKKKEMMIKH IAAEEEKLSI  60
   61 LEDKEMVKEN LQQCKTKLAW MAVTSYQNEL NNLEHSIKLI ENKKASLEQT TSKKESTQAT 120
  121 MNQKLKEFEA SKNQILATQK FQDERLKTAK KAVQDLLLEA SQVKAKIGNA ERRMREDQRS 180
  181 YDECEKLIGN YHADFNRVNE QREENANKIE MLKKQVVKSE EIIAQLRAEQ QEIKRDITSV 240
  241 QERLDAVKNG RIQLHKSKQN ISWEIEALSR NKSNKLSVYG EQTIQVVHAL RTQYAGSNMH 300
  301 RMPRGPLGQY ISAPNPKYRD LIENQLMHCL RSFIVGSDRE RQSLRALLQN KFQGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [605-677]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMPTIITSPF TDRVYDVSRN KVQPTTPNTT VLIDEISCDD PVVMNYLIDI LRIETVLVTE  60
   61 SKEIAEFLTS DTE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [678-968]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVPPNLTRVL VPNLGLEYIP SPNYAVYSTR ITPARYIQKN VDDRIRQLQM EQSDLQEKEP  60
   61 SLEIDYMQHK KVLENTQKVI SQKSTMIGQH QSRNQKAMQK IMELQNFDYQ ELPEYDRLKS 120
  121 HLADSGEKIE KCRLEREMLQ EKLLSIQHRQ TELESTEAEE RRALEGINKK LTALDTEAGE 180
  181 VESKMRSLDL HYEENTRRFQ KTLQLERKML GEKETVLSEL EKARTEAEKL GEFIATTQTE 240
  241 EKIREAISRY KSKIKQVEEL NYNPEELERG LAELRDELEL QSRHLAVVDS V

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.31
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [969-1122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKKLRMAYHQ RAQLFQRSRH HYFTMVQFQF EQALAMRQFK VSFETSDKEK TWKINVFPPS  60
   61 GNETSNTRSL SGGERSFTTV SLLKGLWSTS DHPFYFLDEY DVFTDEVNRK FITEILIGEG 120
  121 LEWLSRQYCF LTPQDTKVEA SNLITVHKLE APER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.154902
Match: 1xewY
Description: Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.
Matching Structure (courtesy of the PDB):

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