| Protein: | Dys-PB |
| Organism: | Drosophila melanogaster |
| Length: | 1669 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dys-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
845.0 | [0..1] | [1669..1] |
|
Region A: Residues: [1-163] |
1 11 21 31 41 51
| | | | | |
1 MTAKPPPPIP PTLGGDDSGT HGPKLAPEIP RINSELAAQA ALRGQQLLRK QGSQEQHATN 60
61 TLPAHKTGAP PPLPPTQSRP VPAIPARGAS DRAAPPEIPP KRHSLKSMPD GQPMMVPGLP 120
121 PTMRQPPPLP RKPASTQSSA QNSAQSSPLA GMKFKDKPPP PPE
|
| Detection Method: |  |
| Confidence: | 6.09691 |
| Match: | 1y0fA |
| Description: | No description for 1y0fA was found. |
|
Region A: Residues: [164-413] |
1 11 21 31 41 51
| | | | | |
1 KHSTLSAEGM AARRCSNPFE MPPPPPPLVL QSAVAALSEQ SSKNGLNPVP SPAPTRASEA 60
61 KKINQRSIAS PTEEFGSEDA LRGIESGLRN MERAMQEQMN LRNMEAAVQN NFDLSFKASL 120
121 AAGARHLGGG SVNLRTANYE RNLSLDEGRA GDSRQSLEEL KQLRAQAQQQ SLLNNSSSSS 180
181 SNSQVEQSMR STIEHHMRSL DRNLPLELQY SRHRFQNNLN AVAAAGGGGG NSSTGNAVAN 240
241 SGTSGSQQPP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [414-866] |
1 11 21 31 41 51
| | | | | |
1 MPLSSEFREQ IRQQLLGNIP PQVVHNMGQS PGSAAAAALL QHQAQSRAAA AAAAAAAAAA 60
61 AAQVAAGSGA LSREELRMRR RSSHDETQLT QNSSGGIQVT RLREHWDETS QCVLQRAAQL 120
121 KNMLSDSQRF EAKRLELEKW LARMEQRAER MGTIATTADI LEAQQKEQKS FHAELHQNKQ 180
181 HFDIFNELTQ KLIAVYPNDD TTRIKKMTEV INQRYANLNS GVINRGKQLH AAVHSLQSFD 240
241 RAMDQFLAFL SETETLCENA ESDIERNPLM FKDLQSEIET HRVVYDRLDG TGRKLLGSLT 300
301 SQEDAVMLQR RLDEMNQRWN NLKSKSIAIR NRLESNSEHW NALLLSLREL TEWVIRKDTE 360
361 LSTLGLGPVR GDAVSLQKQL DDHKAFRRQL EDKRPIVESN LTSGRQYIAN EAAVSDTSDT 420
421 EANHDSDSRY MSAEEQSREL TRSIRREVGK LSE
|
| Detection Method: | |
| Confidence: | 17.39794 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [867-1102] |
1 11 21 31 41 51
| | | | | |
1 QWNNLIDRSD NWKHRLDEYM TKMRQFQKIL EDLSSRVALA EQTKTSWLPP SSVGEANEQM 60
61 QQLQRLRDKM TTASALLDDC NEQQSFFTAN QVLVPTPCLS KLEDLNTRMK LLQIAMDERQ 120
121 KVLCQAGAQQ THENGDDGRT TSNSGTIGPL PNLGQSVKPP WERATTAANV PYYIDHERET 180
181 THWDHPEMIE LMKGLADLNE IRFSAYRTAM KLRSVQKRLA LDRISMSTAC ESFDRH
|
| Detection Method: | |
| Confidence: | 6.39794 |
| Match: | 1u4qA |
| Description: | Crystal Structure of Repeats 15, 16 and 17 of Chicken Brain Alpha Spectrin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1103-1188] |
1 11 21 31 41 51
| | | | | |
1 GLRAQNDKLI DIPDMTTVLH SLYVTIDKID LTLMLDLAIN WILNVYDSQR TGQIRVLSFK 60
61 VGLVLLCKGH LEEKYRYLFR LVADTD
|
| Detection Method: | |
| Confidence: | 5.30103 |
| Match: | 2dfsA |
| Description: | No description for 2dfsA was found. |
|
Region A: Residues: [1189-1279] |
1 11 21 31 41 51
| | | | | |
1 RRADQRRLGL LLHDCIQVPR QLGEVAAFGG SNIEPSVRSC LEQAGISQEA IDGNQDISIE 60
61 LQHFLGWLQH EPQSLVWLPV LHRLAAAEAA K
|
| Detection Method: | |
| Confidence: | 64.69897 |
| Match: | 1eg3A |
| Description: | Dystrophin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| structural constituent of muscle | 5.54109779906915 | bayes_pls_golite062009 |
| acetylcholine transmembrane transporter activity | 4.63361193364389 | bayes_pls_golite062009 |
| actin binding | 3.96919556235483 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.49668552859347 | bayes_pls_golite062009 |
| binding | 3.17556402087346 | bayes_pls_golite062009 |
| microfilament motor activity | 2.9702957313812 | bayes_pls_golite062009 |
| motor activity | 2.57627414053278 | bayes_pls_golite062009 |
| actin filament binding | 2.35534489389161 | bayes_pls_golite062009 |
| myosin binding | 2.34125070430971 | bayes_pls_golite062009 |
| transcription regulator activity | 2.23156041569913 | bayes_pls_golite062009 |
| metal ion binding | 2.11094352721028 | bayes_pls_golite062009 |
| cation binding | 2.11094352721028 | bayes_pls_golite062009 |
| ion binding | 2.10331783734535 | bayes_pls_golite062009 |
| actin-dependent ATPase activity | 2.06646671333275 | bayes_pls_golite062009 |
| DNA binding | 1.73924929536227 | bayes_pls_golite062009 |
| nucleic acid binding | 1.53225451586959 | bayes_pls_golite062009 |
| calcium ion binding | 1.40919295397643 | bayes_pls_golite062009 |
| protein binding | 1.16246005294206 | bayes_pls_golite062009 |
| transporter activity | 1.15928534291452 | bayes_pls_golite062009 |
| actin monomer binding | 0.9954841049256 | bayes_pls_golite062009 |
| nitric-oxide synthase binding | 0.965098383344279 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.945691505472547 | bayes_pls_golite062009 |
| molecular transducer activity | 0.933783050059916 | bayes_pls_golite062009 |
| signal transducer activity | 0.933783050059916 | bayes_pls_golite062009 |
| amine transmembrane transporter activity | 0.717054504236607 | bayes_pls_golite062009 |
| tubulin binding | 0.710693016758742 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.693724160233023 | bayes_pls_golite062009 |
| structural molecule activity | 0.640474644163009 | bayes_pls_golite062009 |
| myosin heavy chain binding | 0.61866037435065 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.45412801027969 | bayes_pls_golite062009 |
| myosin II heavy chain binding | 0.308481284245779 | bayes_pls_golite062009 |
| microtubule binding | 0.278596514315141 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.246383459363256 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.193201281459889 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.116648335890738 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.0305250212662123 | bayes_pls_golite062009 |
|
Region A: Residues: [1280-1372] |
1 11 21 31 41 51
| | | | | |
1 HQAKCNICKE YPIVGFRYRC LKCFNFDMCQ KCFFFGRNAK NHKLTHPMHE YCTTTTSTED 60
61 VRDFTRALKN KFKSRKYFKK HPRVGYLPVQ SVL
|
| Detection Method: | |
| Confidence: | 26.045757 |
| Match: | 2e5rA |
| Description: | No description for 2e5rA was found. |
|
Region A: Residues: [1373-1436] |
1 11 21 31 41 51
| | | | | |
1 EGDALESPAP SPQHTTHQLQ NDMHSRLEMY ASRLAQVEYG GTGSNSTPDS DDEHQLIAQY 60
61 CQAL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1437-1563] |
1 11 21 31 41 51
| | | | | |
1 PGTSNGSAPK SPVQVMAAMD AEQREELEAI IRDLEEENAN LQAEYQQLCS KEQSGMPEDS 60
61 NGMQHSSSSM TGLSGQGEQG QDMMAEAKLL RQHKGRLEAR MQILEDHNRQ LEAQLQRLRQ 120
121 LLDEPNG
|
| Detection Method: | |
| Confidence: | 2.02 |
| Match: | 2fxmA |
| Description: | No description for 2fxmA was found. |
|
Region A: Residues: [1564-1669] |
1 11 21 31 41 51
| | | | | |
1 GGSSATSSGL PSAPGSALNS KPNTLQTRSV TASQLNTDSP AKMNQQNGHY EHNSKNSSGL 60
61 VTVITEQELE SINDDLEDSS SSNTTNTTTT TTTTATTEKT CVELQK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
