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View Structure Prediction Details

Protein: cdi-PA
Organism: Drosophila melanogaster
Length: 1213 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdi-PA.

Description E-value Query
Range
Subject
Range
gi|5453303 - gi|5453303|gb|AAD43525.1|AF139812_1 serine/threonine protein kinase [Drosophila melanogaster]
834.0 [0..1] [1213..1]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNQHSGPG PPSEICGLSV DQVDSSAASP FIWPSTAGMC TTATTVTTST NGDATAEAPV  60
   61 KHQPLHNGGW IGNGLPPAPV TRTISSDRLV TGSSCRAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.045757
Match: 1opkA
Description: Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.85368024495439 bayes_pls_golite062009
binding 1.57485356549468 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [99-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTAVSALYSV DDFVKEKIGS GFFSEVYKVT HRTTGQVMVL KMNQLRANRP NMLREVQLLN  60
   61 KLSHANILSF MGVCVQEGQL HALTEYINGG SLEQLLANKE VVLSATQKIR LALGIARGMS 120
  121 YVHDAGIFHR DLTSKNVLIR NLANDQYEAV VGDFGLAAKI PVKSRKSRLE TVGSPYWVSP 180
  181 ECLKGQWYDQ TSDVFSFGII QCEIIARIEA DPDMMPRTAS FGLDYLAFV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 1wakA
Description: No description for 1wakA was found.

Predicted Domain #3
Region A:
Residues: [328-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELCPMDTPPV FLRLAFYCCL YDAKSRPTFH DATKKLTLLL EKYEHESSA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.1
Match: 2ivsA
Description: No description for 2ivsA was found.

Predicted Domain #4
Region A:
Residues: [377-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GASPLSSLEL INCSPGGSDS ENVTLTPRAS VPTVATICTA PAGTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.154902
Match: 1zmuA
Description: Catalytic and ubiqutin-associated domains of MARK2/PAR-1: Wild type
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [422-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPRHLQEVDE DGFRFPSKKS ASAALPGTPN GSAGSSGFDD HILKSRVRRA TQKLEAEILL  60
   61 HRRSLSENII HFPMHTSPSD KARCHQMQRQ RSSTHSPTPP RQLSSVQLPA TSIPDP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [538-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPLPKPVPAV LTLRKVGDPQ YKPTSEKDHN GSKPNPFEAL AQLRGVKKIL DANPKTYAAG  60
   61 VGDLFSSCFE MLAPFFKELA AMQSKA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [624-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAQGGGTSTE ETSTGNKASA ATPSEPKSLP VSPHMTRKYS AIELRLPQRI SNAAPPAVTS  60
   61 APPPSIALPT DEDDCDDCNS EGEDPDGGGN CADAES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [720-832]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSDDSAVRPS TVPTARKYRA NSLYAHPLFR GSNGTSMKST STGEFESPTL LKASASTITL  60
   61 TASVGATNSC EDLTESARKS KEQASSGATA AVQALPTPMS GCSTRLVETP VSV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [833-936]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSCTDLELDE LKNTCDLNEL KNSCEQLPLK TNLTRRDSIE SGFFSCFNEE SDAAITNNSF  60
   61 GRQLNGIGSL GFGCGGGGNS SNCCYEKLKT QLMLDACVSA DSEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.39794
Match: 1zzpA
Description: Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl
Matching Structure (courtesy of the PDB):

Predicted Domain #10
Region A:
Residues: [937-989]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDKLASLCRC CYYATSTSNA AVTAAAAAAQ QQQQSHLLND TSSTSSSVLL IDN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [990-1096]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPAVIGGNTS SSTALDSMDD LDADIVASRR THQRRYTCHH ALLSGNGSES QMAATASLIN  60
   61 RLALDSEIHT LLQRSPFATN QLLYCKNRTS SIYTDSSDDI SSLAGSD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1097-1213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLLWDDRSFT ALPSTRSAQI AKIVEYFERK RQDSSPPSVH HRNGNGTVAA AVAASALGSN  60
   61 YLSYESRRYS DFKRHLNADG LCFDLDKKPA QQRMMVCEGA VKSKLPIFDK KKQQQGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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