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View Structure Prediction Details

Protein: WRNexo-PA
Organism: Drosophila melanogaster
Length: 353 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WRNexo-PA.

Description E-value Query
Range
Subject
Range
gi|114322007, gi... - gi|78702619|ref|ZP_00867050.1| DNA polymerase A [Alkalilimnicola ehrlichei MLHE-1], gi|78519889|gb|E...
244.0 [0..2] [349..166]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKYLTKMPI KSKANEVPKE EAGVKKETPK VARKATKKDT PKELKDKENA GDDNTPKQTK  60
   61 GRPGRPAAKR KNLDTPDVTE KLAMEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1exnA
Description: T5 5'-exonuclease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.974539540276602 bayes_pls_golite062009
hydrolase activity 0.819924838862535 bayes_pls_golite062009
5'-3' exonuclease activity 0.63821154629201 bayes_pls_golite062009
exonuclease activity 0.51931990830742 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0476541893277298 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENPPKRRSSR LTRSTRSMAE DGSPSPEKEK PEKLPFIKYK GAIKYFTESQ DIAASADDVL  60
   61 QWVEKQKDEV VPMAFDMEWP FSFQTGPGKS AVIQICVDEK CCYIYQLTNV KKLPAALVAL 120
  121 INHPKVRLHG VNIKNDFRKL ARDFPEVTAE PLIEKCVDLG LWCNEVCETG GRWSLERLTN 180
  181 FIAKKAMDKS KKVRMSKWHV IPLDENQLMY AAIDVYIGQV IYRELERREK VKIKNEEEFK 240
  241 EKNGDAAFKA MKALGETFLT KINEVTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.154902
Match: 2fbtA
Description: No description for 2fbtA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle