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View Structure Prediction Details

Protein: CG7156-PA
Organism: Drosophila melanogaster
Length: 681 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG7156-PA.

Description E-value Query
Range
Subject
Range
gi|54639720, gi|... - gi|54639720|gb|EAL29122.1| GA20142-PA [Drosophila pseudoobscura], gi|125778424|ref|XP_001359970.1| G...
339.0 [0..1] [675..1]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLNLGGWIH SFTVTDTQEH KGGYTIYKIT SIVFPRSVPQ ALTCLVVWKR FHDVKRLHRE  60
   61 LSRRHKSLQL PGKLPVPTDS TYFKRFDAAV IQRRKEYILQ LLDFAAQHPA LYKCSTFTQF 120
  121 FQETPSPNGS PLKKLYVERS LRLQTEDNGC GSGGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1xteA
Description: crystal structure of CISK-PX domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.338746218582455 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [156-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETGTCAGAIA DICDKLDLPY DPHDAGGITP LDPRCDKEQT NNESQAKETE IELETK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [212-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEPKTDVALT KRDYLRLLTP MASIESDDSD YIYEAALEFS HAVQAEVNLE YAEAHERYKH  60
   61 GVDLLLNGAK QDSSEERRFI AKAKIAKYLA RAEEIHANFL ANDCP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.07
Match: 2v6xA
Description: No description for 2v6xA was found.

Predicted Domain #4
Region A:
Residues: [317-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKKLQFQLSL DTTDGGSVSH LECPWNQLAR YKVLQILQDR VMQVQCVTKS QQPAAIMKGV  60
   61 EKPASHSLTQ SIFLPQQVPY MVQLLAYFQS EQKIFLLLRQ 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [417-681]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEGGMLYDYL QSYTPTSSKS VNYGELFPSD QEPEEKEAEE PPLTSDSDVS DLVRSSQQLL  60
   61 KSVTNTLSNL QAGVVTPKRN KKVDQNRIRS KPIPEQCLRQ WACELAIAIH SLHGKGVILR 120
  121 DLHMGNILLG AKGQLLLTYF YQNEGLTSDD NYVHKALNLE AVANHFVAPE RPLTFRSDWW 180
  181 SYGVVLYQLL LGVPYKVTHP GQLDLYGCVQ YPSESLEISD HAKDLLEQLL QLSPELRLDY 240
  241 DQLQAHPFFK GIDWQAVLEQ GTESM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.30103
Match: 1gzkA
Description: Pkb kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.686492203566958 bayes_pls_golite062009
transferase activity 0.66841261245817 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.66326000691279 bayes_pls_golite062009
kinase activity 0.65753777854807 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.64444215862273 bayes_pls_golite062009
protein kinase activity 0.56587465829201 bayes_pls_golite062009
binding 0.0554152720226 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle