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View Structure Prediction Details

Protein: Prx5037-PA
Organism: Drosophila melanogaster
Length: 234 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Prx5037-PA.

Description E-value Query
Range
Subject
Range
gi|125773251|ref... - GA19159-PA [Drosophila pseudoobscura], GA19159 [Drosophila pseudoobscura pseudoobscura]
gi|125773251, gi... - gi|54637618|gb|EAL27020.1| GA19159 [Drosophila pseudoobscura pseudoobscura], gi|125773251|ref|XP_001...
gi|195158357, gi... - gi|195158357|ref|XP_002020058.1| GL13701 [Drosophila persimilis], gi|194116827|gb|EDW38870.1| GL1370...
254.0 [0..1] [234..1]

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Predicted Domain #1
Region A:
Residues: [1-234]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFVARSLIR NVPLMGKAIL SQQKQIAARL LHQTAPLAAV RVQQPAPDFK GLAVVDNSFQ  60
   61 EVKLEDYRGK YLVLFFYPLD FTFVCPTEIV AFSERIKEFH DINTEVLGVS VDSHFSHLTW 120
  121 CNVDRKNGGV GQLKYPLLSD LTKKISADYD VLLDKEGISL RGTFIIDPNG ILRQYSINDL 180
  181 PVGRSVDEVL RLIKAFQFVE QHGEVCPANW NPNSNPATIK PDVEESKKYF SKHG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.0
Match: 1qmvA
Description: Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alkyl hydroperoxide reductase activity 4.29610283853788 bayes_pls_golite062009
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
selenium binding 2.92496040718744 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
transcription regulator activity 2.30799114442278 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
transferase activity 1.26687471229876 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
protein binding 1.18479617596618 bayes_pls_golite062009
molecular transducer activity 1.11518182894524 bayes_pls_golite062009
signal transducer activity 1.11518182894524 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
peptide binding 0.374493676068876 bayes_pls_golite062009
0.359224524631956 bayes_pls_golite062009
NADH dehydrogenase activity 0.23291471505999 bayes_pls_golite062009
copper ion binding 0.178842772364502 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 0.16328723676608 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 0.0434052164026002 bayes_pls_golite062009

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