YRC Public Data Repository - Protein Structure Prediction

Protein:	FBpp0307971, CG5...
Organism:	Drosophila melanogaster
Length:	160 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0307971, CG5....

Description	E-value	Query Range	Subject Range
gi\|54307981, gi\|... - gi\|54307981\|ref\|YP_129001.1\| putative cytosine/adenosine deaminase [Photobacterium profundum SS9], g...	183.0	[0..2]	[160..11]
gi\|116184449 - gi\|116184449\|ref\|ZP_01474386.1\| hypothetical protein VEx2w_02003038 [Vibrio sp. Ex25]	181.0	[0..2]	[160..32]
gi\|71145999, gi\|... - gi\|71280259\|ref\|YP_270337.1\| cytidine/deoxycytidylate deaminase zinc-binding domain-containing prote...	181.0	[0..4]	[145..25]
gi\|77974711 - gi\|77974711\|ref\|ZP_00830250.1\| COG0590: Cytosine/adenosine deaminases [Yersinia frederiksenii ATCC 3...	180.0	[0..2]	[157..35]
gi\|77978398 - gi\|77978398\|ref\|ZP_00833827.1\| COG0590: Cytosine/adenosine deaminases [Yersinia intermedia ATCC 2990...	180.0	[0..2]	[160..33]
gi\|77809323, gi\|... - gi\|77815675\|ref\|ZP_00814899.1\| Cytidine/deoxycytidylate deaminase, zinc-binding region [Shewanella p...	179.0	[0..2]	[160..10]
gi\|52306511, gi\|... - gi\|52424459\|ref\|YP_087596.1\| hypothetical protein MS0404 [Mannheimia succiniciproducens MBEL55E], gi...	179.0	[0..2]	[156..9]
gi\|16761480 - gi\|16761480\|ref\|NP_457097.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enterica ... TADA_SALTI - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Salmonella typhi gi\|16421115, gi\|... - gi\|16765888\|ref\|NP_461503.1\| tRNA-specific adenosine deaminase [Salmonella typhimurium LT2], gi\|1642... TADA_SALTY - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Salmonella typhimurium gi\|29136448, gi\|... - gi\|29140823\|ref\|NP_804165.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enterica ... gi\|62181133, gi\|... - gi\|62181133\|ref\|YP_217550.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enterica ... lcl\|NC_016856.1_... - [gene=yfhC] [protein=tRNA-specific adenosine deaminase] [protein_id=YP_005238675.1] [location=comple... gi\|16503780, gi\|... - gi\|25303877\|pir\|\|AF0827 conserved hypothetical protein STY2814 [imported] - Salmonella enterica subs... gi\|224582890, gi... - gi\|224582890\|ref\|YP_002636688.1\| hypothetical protein SPC_1081 [Salmonella enterica subsp. enterica ...	178.0	[0..2]	[160..20]
TADA_SHIFL - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Shigella flexneri gi\|218352918, gi... - gi\|218696186\|ref\|YP_002403853.1\| tRNA-specific adenosine deaminase [Escherichia coli 55989], gi\|2183... gi\|24113886, gi\|... - gi\|24113886\|ref\|NP_708396.1\| tRNA-specific adenosine deaminase [Shigella flexneri 2a str. 301], gi\|2... gi\|218361852, gi... - gi\|218555084\|ref\|YP_002387997.1\| tRNA-specific adenosine deaminase [Escherichia coli IAI1], gi\|21836... gi\|254289295, gi... - gi\|254289295\|ref\|YP_003055043.1\| tRNA-specific adenosine deaminase [Escherichia coli BL21(DE3)], gi\|... gi\|218547914, gi... - gi\|218547914\|ref\|YP_002381705.1\| tRNA-specific adenosine deaminase [Escherichia fergusonii ATCC 3546... YFHC_ECOLI, TADA... - (P30134) Hypothetical protein yfhC, tRNA-specific adenosine deaminase (EC 3.5.4.-) - Escherichia col... gi\|209920038, gi... - gi\|209920038\|ref\|YP_002294122.1\| tRNA-specific adenosine deaminase [Escherichia coli SE11], gi\|20991... gi\|30042202, gi\|... - gi\|30063946\|ref\|NP_838117.1\| tRNA-specific adenosine deaminase [Shigella flexneri 2a str. 2457T], gi... gi\|82545011, gi\|... - gi\|82545011\|ref\|YP_408958.1\| tRNA-specific adenosine deaminase [Shigella boydii Sb227], gi\|81246422\|... gi\|1788911, gi\|1... - gi\|1788911\|gb\|AAC75612.1\| tRNA-specific adenosine deaminase [Escherichia coli K12], gi\|16130484\|ref\|... gi\|85675450, gi\|... - gi\|89109365\|ref\|AP_003145.1\| tRNA-specific adenosine deaminase [Escherichia coli str. K-12 substr. W... gi\|157067716, gi... - gi\|157162036\|ref\|YP_001459354.1\| tRNA-specific adenosine deaminase [Escherichia coli HS], gi\|1570677... gi\|1033148\|gb\|AA... - alternate name yfhC; orf178 of GenBank Accession Number X72336 gi\|188491218, gi... - gi\|188496019\|ref\|ZP_03003289.1\| tRNA-specific adenosine deaminase [Escherichia coli 53638], gi\|18849... gi\|187427445, gi... - gi\|187730453\|ref\|YP_001881338.1\| tRNA-specific adenosine deaminase [Shigella boydii CDC 3083-94], gi... gi\|253974435, gi... - gi\|254162534\|ref\|YP_003045642.1\| tRNA-specific adenosine deaminase [Escherichia coli B str. REL606],... gi\|251785887, gi... - gi\|251785887\|ref\|YP_003000191.1\| hypothetical protein B21_02417 [Escherichia coli BL21], gi\|24237816...	178.0	[0..2]	[159..20]
gi\|90438699, gi\|... - gi\|90579814\|ref\|ZP_01235622.1\| Putative cytosine/adenosine deaminase [Vibrio angustum S14], gi\|90438...	178.0	[0..2]	[160..11]

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Predicted Domain #1

Region A:
Residues: [1-160]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAFMEEALV EARRARDAGE VPVGCVFVHG DKVVARGGNE VNVHRNATRH AEFICIDAIL  60
   61 ASCRERRLPA RQLFSEITVV VTVEPCIMCS AALHTLGVKE IIYGCENDRF GGKTVVDVAA 120
  121 VVGHRIEITG GVRADEAMAL LKDFYKGDNP AAPPQAKKKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.0
Match:	1z3aA
Description:	Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytidine deaminase activity	4.42667374679603	bayes_pls_golite062009
deaminase activity	2.76997916054448	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.27736397496642	bayes_pls_golite062009
catalytic activity	1.70756445127105	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.51294035758003	bayes_pls_golite062009
methyltransferase activity	1.24697538679504	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.16679252289538	bayes_pls_golite062009
IMP cyclohydrolase activity	1.11605611485835	bayes_pls_golite062009
binding	1.05190374148481	bayes_pls_golite062009
phosphoribosylaminoimidazolecarboxamide formyltransferase activity	0.827438033765078	bayes_pls_golite062009
transferase activity	0.771056210634777	bayes_pls_golite062009
hydrolase activity	0.452099352697972	bayes_pls_golite062009
cyclohydrolase activity	0.308525511259279	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	0.1546696349714	bayes_pls_golite062009
protein binding	0.095488575269861	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: