YRC Public Data Repository - Protein Structure Prediction

Protein:	Dhfr-PB, Dhfr-PA
Organism:	Drosophila melanogaster
Length:	182 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dhfr-PB, Dhfr-PA.

Description	E-value	Query Range	Subject Range
gi\|500630, gi\|10... - gi\|500630\|gb\|AAA19051.1\| dihydrofolate reductase, pir\|\|A53803 dihydrofolate reductase (EC 1.5.1.3) -...	209.0	[0..1]	[182..1]
gi\|54639130, gi\|... - gi\|54639130\|gb\|EAL28532.1\| GA13324-PA [Drosophila pseudoobscura], gi\|125776766\|ref\|XP_001359386.1\| G...	201.0	[0..1]	[180..1]
DYR_PIG - Dihydrofolate reductase OS=Sus scrofa GN=DHFR PE=1 SV=1 gi\|66093 - pir\|\|RDPGD dihydrofolate reductase (EC 1.5.1.3) - pig	201.0	[0..2]	[182..2]
gi\|85658490, gi\|... - gi\|88601320\|tpd\|FAA00073.1\| TPA: dihydrofolate reductase [Cricetulus griseus], gi\|85658490\|dbj\|BAE78... gi\|304502 - gi\|304502\|gb\|AAA36970.1\| dihydrofolate reductase (EC 1.5.1.3)	199.0	[0..2]	[181..3]
DYR_RAT - Dihydrofolate reductase OS=Rattus norvegicus GN=Dhfr PE=2 SV=3	199.0	[0..2]	[181..3]
AGAP010278-PA - dihydrofolate reductase\|protein_coding\|3R:51946735:51947367:-1\|gene:AGAP010278 gi\|116118563, gi... - gi\|119114744\|ref\|XP_319471.3\| AGAP010278-PA [Anopheles gambiae str. PEST], gi\|116118563\|gb\|EAA14339....	198.0	[0..3]	[181..4]
gi\|21702230 - gi\|21702230\|emb\|CAD38046.1\| dihydrofolate reductase-thymidylate synthase [Pisum sativum]	198.0	[0..2]	[180..25]
DYR_MOUSE - Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=1 SV=3	198.0	[0..2]	[181..3]
DYR_AEDAL - Dihydrofolate reductase OS=Aedes albopictus GN=DHFR PE=3 SV=1	197.0	[0..1]	[180..1]

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Predicted Domain #1

Region A:
Residues: [1-182]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRFNLIVAV CENFGIGIRG DLPWRIKSEL KYFSRTTKRT SDPTKQNAVV MGRKTYFGVP  60
   61 ESKRPLPDRL NIVLSTTLQE SDLPKGVLLC PNLETAMKIL EEQNEVENIW IVGGSGVYEE 120
  121 AMASPRCHRL YITKIMQKFD CDTFFPAIPD SFREVAPDSD MPLGVQEENG IKFEYKILEK 180
  181 HS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.045757
Match:	2fzjA
Description:	No description for 2fzjA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits