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View Structure Prediction Details

Protein: CG5044-PB
Organism: Drosophila melanogaster
Length: 386 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5044-PB.

Description E-value Query
Range
Subject
Range
gi|220946432 - gi|220946432|gb|ACL85759.1| CG5044-PA [synthetic construct]
CG5044-PA - This gene is referred to in FlyBase by the symbol Dmel\CG5044 (CG5044, FBgn0038326). It is a protein...
367.0 [0..3] [386..2]

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Predicted Domain #1
Region A:
Residues: [1-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQGPIQRLVY TFGHRTCSQL PMIGGATISQ TKPTTMALSV RQSSSSVLAT ESSNKGMIIL  60
   61 NRPKALNAIN LEMVRKIYKH LKKCEKSKSL VIIKGTGDKA FCAGGDVRAL VEAGPTDESK 120
  121 SFFREEYSTN ALIGNYKIPY IAIIDGITMG GGVGLSVHGK YRVASDRTLF AMPETAIGLF 180
  181 PDVGGSYFLP RLQGKLGLYL GLTGYRLRGA DVYYSGIATH YCESSKIPDL ETALLNCPDA 240
  241 DDVPELLQKY HSPPEKPFSL QPVLEQINKN FSADSVEGIL ENLQNDGSEW AKKTLETLSK 300
  301 MSPTSMKVTF RQLELGSQLS LAQCLIMEYR LAVRHLERSD FKEGVRALLI DKDQKPQWQP 360
  361 TKLADVTEEH VQWFFRKLPD TEELKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.0
Match: 1wdkA
Description: fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
CoA carboxylase activity 2.59376553092594 bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds 2.5107600311009 bayes_pls_golite062009
enoyl-CoA hydratase activity 2.49886494691134 bayes_pls_golite062009
acetyl-CoA carboxylase activity 2.35262768569224 bayes_pls_golite062009
catalytic activity 1.46154163027498 bayes_pls_golite062009
dodecenoyl-CoA delta-isomerase activity 1.06414044115735 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 0.981631877562763 bayes_pls_golite062009
ligase activity 0.393388746635198 bayes_pls_golite062009
propionyl-CoA carboxylase activity 0.2998946244546 bayes_pls_golite062009
3-hydroxybutyryl-CoA epimerase activity 0.241955774397835 bayes_pls_golite062009
binding 0.106191992778711 bayes_pls_golite062009
racemase and epimerase activity, acting on hydroxy acids and derivatives 0.099208209617217 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle