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View Structure Prediction Details

Protein: mthl5-PA
Organism: Drosophila melanogaster
Length: 496 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mthl5-PA.

Description E-value Query
Range
Subject
Range
gi|21464400 - gi|21464400|gb|AAM52003.1| RE27241p [Drosophila melanogaster]
264.0 [0..1] [496..1]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVKTLGAHF AAGQNAKKCS CCALLISLLC VLLLSLNPLP VTSHVTSAGS STALSSDPNL  60
   61 VLVNKCCEKF EIHVDHECQQ VNETDYFQPM FTSYGGEQNR PVKFKFVIGI PNCGSMQMWP 120
  121 IYHYAGSSDK LVLLDDGRLR HYTNAENEAE ERHGIQSDYE EDIAGSLEPL YHDYDKGLYC 180
  181 IDK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.154902
Match: 1fjrA
Description: Methuselah ectodomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
G-protein coupled receptor activity 7.48253527316663 bayes_pls_golite062009
transmembrane receptor activity 5.76968261800439 bayes_pls_golite062009
receptor activity 5.47976284348283 bayes_pls_golite062009
signal transducer activity 4.51388461085202 bayes_pls_golite062009
molecular transducer activity 4.51388461085202 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [184-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATSSTGEENV LFANICLARK EIKWSDSNFL LRKILNPIFH GISLVILLVI AIIYFILPTL  60
   61 RDLVGNIVTT IAMCLMVSQA ADLVRIFTEL TSHVSFIVAD IILCFSLLAA FFWLNSFGFY 120
  121 IWKTFRSRNV FLRVTDGRKY CYYSAYAWGC TATMAALAVF AHFFLDAESY KQEHMVGEQE 180
  181 TIGWLGICIF FAPIACTILV NIFFYVTTRK LINRRTVYGR IAHKLKANFI MFSLMLLVMS 240
  241 IAWLFLIMSW LQMEGLLYAH IVVNALQTPL LLYICVLRQR HVTFLLKKTC CYNEPPSAND 300
  301 WGDELHYMNG NDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 2j4yA
Description: No description for 2j4yA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle