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View Structure Prediction Details

Protein: CG31116-PA
Organism: Drosophila melanogaster
Length: 1176 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31116-PA.

Description E-value Query
Range
Subject
Range
gi|21428948 - gi|21428948|gb|AAM50193.1| GH23529p [Drosophila melanogaster]
860.0 [0..1] [1176..1]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNNSHSHQD EYIREYAFEP ELLINREDYQ RKEERSQKST AASSASTPVR QRWDEVIAKQ  60
   61 KEQQRKQSIE IDPPGDDKNQ IEIEIEAFYY MYGRYTKDLG EFAKDEARKL KILEKRRKQE 120
  121 DKQRNKELLG KHSTRAKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [139-655]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSSWIWRHTV ARLGEDWVFL ALLGIIMALL SFIMDKGISI CTNARIWLYR DLTSQPFVQY  60
   61 IAWVSLPVCL ILFSAGFVHL IAPQSIGSGI PEMKTILRGV QLKEYLTFKT LVAKVIGLTA 120
  121 TLGSGMPLGK EGPFVHIASI VAQLLSKLVT SFQGIYENES RNSEMLAAAC AVGVGACFAA 180
  181 PVGGVLFSIE VTTTYFAVRN YWRGFFAAVC GATVFRLLAV WFQNADTVRA LFLTNFTTEF 240
  241 PFDPQELFVF ALIGLVCGLG GASYVWVHRR YVLFMRSNKR MNKFLQKNRF LYPGFLALLV 300
  301 SSISFPLGTG QFLAGELSTH EQVTQLFSNF TWSRDDLTVE QAAVVTHWMT SYTSVFGNLV 360
  361 IYTLFTFVVS IIASTIPVPS GMFIPVFKIG AGFGRLVGEF MAVTFPHGVR YGGRLSPIMP 420
  421 GGYAVVGAAA FSGSVTHTVS VAVIIFEMTG QITHVVPVMI AVLVANAVAA LLQPSIYDSI 480
  481 ILIKKLPYLP DLLPSSSGMY SIFVEDFMVR DVKYIWH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.0
Match: 1occA
Description: Mitochondrial cytochrome c oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ion transmembrane transporter activity 4.88027604120114 bayes_pls_golite062009
cation transmembrane transporter activity 4.53505586520514 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.48195996846249 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 4.23827260313614 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 3.88623405655787 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 3.8080656397351 bayes_pls_golite062009
transporter activity 3.02642879486966 bayes_pls_golite062009
transmembrane transporter activity 2.89692543447799 bayes_pls_golite062009
substrate-specific transporter activity 2.65243944674297 bayes_pls_golite062009
binding 0.89004160546195 bayes_pls_golite062009
heme-copper terminal oxidase activity 0.495729272244233 bayes_pls_golite062009
protein binding 0.358081002328109 bayes_pls_golite062009
cytochrome-c oxidase activity 0.0861647825336554 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 0.0861647825336554 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 0.0861647825336554 bayes_pls_golite062009
copper ion binding 0.0276945807548814 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [656-943]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GISYQKLKEV LKLNKTLRSL PLVDSPDNMI LLGSVQRYEL IKMIEKHIGR EKRMEVAQKW  60
   61 QKEAQERALE EEKKKQEVEL KMRRPSRFEV LPAPDILSLR QIANDEMLPP KKRAETMHGS 120
  121 LAPRKSILKK TNSFNLKTYA QPMGHSPSIT PYTTITGNSE FRIRSAFEAI FKKSTTLQDV 180
  181 QPDPETGSLS PAASNHEVEV PRTPSTPGVS KKVQLPAQSN WDFVTDQIML QVNPISTESN 240
  241 KMPAEKDFTD KALSNNGDSS KQSPSIKFKA NKVADVNRSP QTAKRCSK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.86
Match: 2d4zA
Description: Crystal structure of the cytoplasmic domain of the chloride channel ClC-0
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [944-1097]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRFANEVGVN GSPTRTKCKI KPENVLGYSI EDVDETTNPE SLAESIQKPK SVRLPRERVI  60
   61 DMSPEDQKQW ELEEMLKPID LQKANVHIDP SPFQLVERTS ILKVHSLFSM VGINHAYVTK 120
  121 IGRLVGVVGL KELRKAIEDI NSNSFVPPTR DEDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.154902
Match: 2d4zA
Description: Crystal structure of the cytoplasmic domain of the chloride channel ClC-0
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [1098-1176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEKPAVEKPL LSTNSSDKAV DMTVTSMDSA LSNSENCSDI EMEHIKHTDK GTVSLTMPPQ  60
   61 ESKQSPSADK SNTENGNHA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle