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View Structure Prediction Details

Protein: CG6567-PB
Organism: Drosophila melanogaster
Length: 235 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6567-PB.

Description E-value Query
Range
Subject
Range
gi|109086409 - gi|109086409|ref|XP_001083287.1| PREDICTED: lysophospholipase I isoform 2 [Macaca mulatta]
157.0 [0..2] [228..8]
LYPA1_PONPY - Acyl-protein thioesterase 1 - Pongo pygmaeus (Orangutan)
LYPA1_PONAB - Acyl-protein thioesterase 1 OS=Pongo abelii GN=LYPLA1 PE=2 SV=1
156.0 [0..2] [228..8]
gi|50737613 - gi|50737613|ref|XP_419203.1| PREDICTED: similar to Acyl-protein thioesterase 1 (Lysophospholipase I)...
156.0 [0..2] [228..8]
gi|114620143 - gi|114620143|ref|XP_519760.2| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes]
156.0 [0..2] [228..8]
gi|123996083, gi... - gi|123996083|gb|ABM85643.1| lysophospholipase I [synthetic construct], gi|123981248|gb|ABM82453.1| l...
LYPLA1 - lysophospholipase I
156.0 [0..2] [228..8]
LYPA1_RABIT - Acyl-protein thioesterase 1 OS=Oryctolagus cuniculus GN=LYPLA1 PE=1 SV=1
LYPA1_MOUSE - Acyl-protein thioesterase 1 OS=Mus musculus GN=Lypla1 PE=1 SV=1
155.0 [0..2] [228..8]

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Predicted Domain #1
Region A:
Residues: [1-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPALTTVNA TGKHTASVIF FHGSGDTGPN VLEWVRFLIG RNLEYPHIKI IYPTAPKQKY  60
   61 TPLDGELSNV WFDRKSVNIA ASESKKSMSQ CYDAVNQLID EEVASGIPLN RIVVGGFSMG 120
  121 GALALHTGYH LRRSLAGVFA HSSFLNRGSV VYDSLANGKD ESFPELRMYH GERDTLVPKD 180
  181 WGLETFENLT KLGVKGTFHP LRNTLHELKT ASITDLQQWI YEKLPPLENQ VQNKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.522879
Match: 1fj2A
Description: Acyl protein thioesterase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.24106351016868 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.09488027320166 bayes_pls_golite062009
lipase activity 0.849473630399459 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity 0.277033874372149 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle