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View Structure Prediction Details

Protein: cwo-PA
Organism: Drosophila melanogaster
Length: 698 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cwo-PA.

Description E-value Query
Range
Subject
Range
FBpp0293681, FBp... - type=protein; loc=3R:join(6223133..6223406,6223469..6225060); ID=FBpp0293682; name=cwo-PC; parent=FB...
186.0 [0..78] [698..1]

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Predicted Domain #1
Region A:
Residues: [1-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPYWNETNG HAAHPVKYES EAAVSSFPYC TESSLNFSTS ATAYSEDDAE YATGRRNKTS  60
   61 RQDPLSHRII EKRRRDRMNS CLADLSRLIP PQYQRKGRGR IEKTEIIEMA IRHLKHLQSE 120
  121 CQQKESDYRS GYMDCMKEAA KFLYD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.30103
Match: 1an4A
Description: Usf B/HLH domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.04189889011459 bayes_pls_golite062009
DNA binding 1.47769879162301 bayes_pls_golite062009
transcription regulator activity 1.40297587472455 bayes_pls_golite062009
transcription factor activity 1.37196407054029 bayes_pls_golite062009
nucleic acid binding 1.25065254420125 bayes_pls_golite062009
protein binding 0.90375176425983 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [146-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHMQDFCHRL LGRLQEHIDE MFKTDCYKST RSCHMPDNVS ASSGSPHQAY HPPLCHLRDM  60
   61 LATSASDVEH SQDHNDVKDL SFRNHLNQLQ RSQQAAAAAA VAAAAVAVAN GSSPASNAGV 120
  121 DSKVPLTNGG GTGGAPPAAD NVPSNSTGSG SAAACAGGNS NSSGSNSSNA ASSTICPPAG 180
  181 GSCPAK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [332-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTPLAAHQQP HQAPVITSTA PHHHHHHTDS SHHDFESSRE PILHTDTSNM HSPPPRDLLL  60
   61 QQHPHLAHSH HTQDSLMSVR MRNYSESSHE IEHNNNYKYK NHIKERFVHE LHDEETSSEH 120
  121 CPVAAHLQSD HSHLQALSEH SK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [474-698]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGTEPEIAPI MAKKRKLAEA AANGEIPLEV HTESSNAGAS SANRLDKPSP SFNFSDIKDI  60
   61 KAELHNGNSN SSPLLAKLSA VAAAGGQLST PSSTTAPLPP RHTFTVPIFA LHGQGNYYVP 120
  121 LNVDYNALVP FLNGMDLLEK SYTSMPVVHP ININVNFMPS SPSASLLAAA AAAAVAVGKQ 180
  181 QQQQAVVAAG AGLPLSTNSA AAQAAAVAAA AVAKAKLEQA MNQSW

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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