YRC Public Data Repository - Protein Structure Prediction

Protein:	FBpp0297149, SpdS-PA
Organism:	Drosophila melanogaster
Length:	287 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0297149, SpdS-PA.

Description	E-value	Query Range	Subject Range
gi\|531202, gi\|45... - gi\|531202\|gb\|AAA36633.1\| spermidine synthase, ref\|NP_003123.1\| spermidine synthase [Homo sapiens]	237.0	[0..3]	[287..15]
SPD1_ARATH - Spermidine synthase 1 OS=Arabidopsis thaliana GN=SPDSYN1 PE=1 SV=1	236.0	[0..2]	[286..41]
gi\|114553926 - gi\|114553926\|ref\|XP_514381.2\| PREDICTED: spermidine synthase isoform 3 [Pan troglodytes]	236.0	[0..3]	[287..15]
gi\|108997020 - gi\|108997020\|ref\|XP_001102838.1\| PREDICTED: spermidine synthase [Macaca mulatta]	236.0	[0..3]	[287..15]
SPEE_MOUSE - Spermidine synthase OS=Mus musculus GN=Srm PE=1 SV=1	236.0	[0..3]	[287..15]
gi\|13384156, gi\|... - gi\|16758208\|ref\|NP_445916.1\| spermidine synthase [Rattus norvegicus], gi\|13384156\|gb\|AAK21288.1\|AF33...	235.0	[0..3]	[287..15]
gi\|23495354 - gi\|23495354\|dbj\|BAC20171.1\| spermidine synthase [Malus x domestica]	235.0	[0..1]	[286..45]
gi\|76637216 - gi\|76637216\|ref\|XP_582280.2\| PREDICTED: similar to spermidine synthase isoform 1 [Bos taurus]	234.0	[0..3]	[287..15]

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Predicted Domain #1

Region A:
Residues: [1-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSLNNGWFS ELQADLWPGQ SFSLKVKEVI HKEKSRFQDI QIVETETYGR CLILDGIIQC  60
   61 TARDEFSYQE MISFLPLCAH PNPKKVLIVG GGDGGVAREV VKHPLVEEVH QVEIDDRVVE 120
  121 LSKQYLPAMA CGFANEKLKL TIGDGFDYMK KHKNEFDVII TDSSDPIGPA VSLFQESYYE 180
  181 LMKHALKDDG IVCSQGGSFW LDLDYIKKTM SGCKEHFAKV AYAVTSVPSY PCGHIGFVMG 240
  241 SLNKNQDFAT PKLGKSEIDS IDLRYYSSEV HSAAFALPRW VQKHFYE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.221849
Match:	2o05A
Description:	No description for 2o05A was found.

Predicted functions:

Term	Confidence	Notes
spermidine synthase activity	2.31131562815571	bayes_pls_golite062009
transferase activity	1.77671966857605	bayes_pls_golite062009
transcription regulator activity	1.61435611638306	bayes_pls_golite062009
DNA binding	1.53375495589674	bayes_pls_golite062009
nucleic acid binding	1.31440474302645	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
binding	0.976078016260105	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.837368219068434	bayes_pls_golite062009
N-methyltransferase activity	0.69697643153076	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.644010137949015	bayes_pls_golite062009
methyltransferase activity	0.635463629299812	bayes_pls_golite062009
protein methyltransferase activity	0.57386401278889	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: