YRC Public Data Repository - Protein Structure Prediction

Protein:	CG11967-PA
Organism:	Drosophila melanogaster
Length:	255 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11967-PA.

Description	E-value	Query Range	Subject Range
gi\|125776717, gi... - gi\|54639112\|gb\|EAL28514.1\| GA11301 [Drosophila pseudoobscura pseudoobscura], gi\|125776717\|ref\|XP_001... gi\|194112243, gi... - gi\|195152523\|ref\|XP_002017186.1\| GL22171 [Drosophila persimilis], gi\|194112243\|gb\|EDW34286.1\| GL2217... gi\|54639112\|gb\|E... - GA11301-PA [Drosophila pseudoobscura], GA11301 [Drosophila pseudoobscura pseudoobscura]	246.0	[0..1]	[255..1]
gi\|9945929, gi\|1... - gi\|9945929\|gb\|AAG03492.1\|AE004449_1 probable carbonic anhydrase [Pseudomonas aeruginosa PAO1], gi\|15... gi\|11351140 - pir\|\|C83631 probable carbonic anhydrase PA0102 [imported] - Pseudomonas aeruginosa (strain PAO1)	244.0	[0..1]	[255..22]
gi\|94416100 - gi\|94416100\|ref\|ZP_01295931.1\| hypothetical protein PaerP_01002180 [Pseudomonas aeruginosa PA7]	243.0	[0..1]	[255..18]
gi\|49082084 - gi\|49082084\|gb\|AAT50442.1\| PA0102 [synthetic construct]	243.0	[0..1]	[255..22]
gi\|117957967 - gi\|117957967\|gb\|ABK59322.1\| beta carbonic anhydrase [Anopheles gambiae] gi\|55241763, gi\|... - gi\|57968460\|ref\|XP_563117.1\| AGAP002992-PA [Anopheles gambiae str. PEST], gi\|55241763\|gb\|EAL40795.1\|...	243.0	[0..1]	[255..1]
gi\|126169587, gi... - gi\|254237656\|ref\|ZP_04930979.1\| hypothetical protein PACG_03741 [Pseudomonas aeruginosa C3719], gi\|1... gi\|115589044, gi... - gi\|116053823\|ref\|YP_788260.1\| carbonic anhydrase [Pseudomonas aeruginosa UCBPP-PA14], gi\|115589044\|g... gi\|254243209, gi... - gi\|254243209\|ref\|ZP_04936531.1\| hypothetical protein PA2G_04014 [Pseudomonas aeruginosa 2192], gi\|19... gi\|218769070, gi... - gi\|218888847\|ref\|YP_002437711.1\| putative carbonic anhydrase [Pseudomonas aeruginosa LESB58], gi\|218...	242.0	[0..1]	[255..22]
gi\|255055897, gi... - gi\|255055897\|ref\|ZP_05308122.1\| Carbonate dehydratase [Pectobacterium wasabiae WPP163], gi\|254988268... gi\|50122249, gi\|... - gi\|50122249\|ref\|YP_051416.1\| carbonic anhydrase [Pectobacterium atrosepticum SCRI1043], gi\|49612775\|...	240.0	[0..1]	[248..4]
gi\|62178741, gi\|... - gi\|62178741\|ref\|YP_215158.1\| putative carbonic anhydrase [Salmonella enterica subsp. enterica serova... gi\|205347482, gi... - gi\|205360728\|ref\|ZP_02685949.2\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar H...	238.0	[0..1]	[248..21]
gi\|85058461, gi\|... - gi\|85058461\|ref\|YP_454163.1\| carbonic anhydrase [Sodalis glossinidius str. 'morsitans'], gi\|84778981...	237.0	[0..1]	[255..4]
gi\|75854184, gi\|... - gi\|75854184\|ref\|ZP_00761894.1\| COG0288: Carbonic anhydrase [Vibrio sp. Ex25], gi\|254230326\|ref\|ZP_04... gi\|91187816, gi\|... - gi\|91228633\|ref\|ZP_01262550.1\| putative carbonic anhydrase [Vibrio alginolyticus 12G01], gi\|91187816...	237.0	[0..1]	[248..4]

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Predicted Domain #1

Region A:
Residues: [1-255]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERILRGIMR YRNTTREQMV KEFQKVRDNP EPKAVFFTCM DSRMIPTRYT DTHVGDMFVV  60
   61 RNAGNLIPHA QHFQDEYFSC EPAALELGCV VNDIRHIIVC GHSDCKAMNL LYQLRDPDFA 120
  121 SKLNRRLSPL RSWLCTHANT SLERFQEWRD AGMKDPLIFS SETPLRRFVA YIDEEQKFAL 180
  181 EDKLSQINTL QQMSNIASYG FLKARLESHD LHIHALWFDI YTGDIYYFSR GAKRFLPVDE 240
  241 DTVDRLSEEV RRFYS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.69897
Match:	1i6oA
Description:	beta-carbonic anhydrase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbonate dehydratase activity	2.96380803089124	bayes_pls_golite062009
catalytic activity	1.85658156053797	bayes_pls_golite062009
carbon-oxygen lyase activity	1.691366175135	bayes_pls_golite062009
hydro-lyase activity	1.65497918079842	bayes_pls_golite062009
lyase activity	1.62374861994341	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: