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View Structure Prediction Details

Protein: Hpr1-PA
Organism: Drosophila melanogaster
Length: 701 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hpr1-PA.

Description E-value Query
Range
Subject
Range
gi|76651775, gi|... - gi|76651775|ref|XP_870010.1| PREDICTED: similar to THO complex subunit 1 (Tho1) (Nuclear matrix prot...
771.0 [0..10] [691..2]

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Predicted Domain #1
Region A:
Residues: [1-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAVEVANT APEKLANYFA LQSAFEKALE LAITDGKVEL LVKEYNRFPA NTEHDKRLPM  60
   61 DHAFRVLLMK RLDEDVSRIG ELVRLSVEAT RAEIVSNTIP VVLLIDTFDV VTLDKCQKIF 120
  121 QFVEDMVEVW KEEIFFSSCK NNILRMCNDL LRRLSRTQNT VFCGRIQLFL SKFFPFSERS 180
  181 GLNIV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [186-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEFNLDNFTE YGLDSKDHDE SDNKELEDTA EDIPLKIDYD LYCKFWSLQD FFRNPNQCYN  60
   61 KPQWKMFQMH ADNILQSFSS FKLEDVRQSS NENASGTDQA MDVDEEAVD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [295-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTAVSSVIKA NHFFAKFLTN PKLLALQLSD ANFRRAVLVQ FLILFQYLQV SVKFKSDTQT  60
   61 LTADQADFIK ETESRVYKLL EETPPYGKRF SRTVYHMLAR EEMWNNWKNE GCKEFKKPEE 120
  121 PTLSEEDSKP TPNKRPRRPL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [435-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDALRDASRS GKFYLGNDNL TRLWNYSPDN LQACKSEQRN FLPLLETYLE TPHEKVDPAF  60
   61 EWRALRLLAR QTPHFFTSLS QPSSKISDYL EQVRKRLIRD KEPKPAALLS NNSSENNFGL 120
  121 SVNNVHTEGE QDATVALQDG EPEQDLEVED NEPVVEEVD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [594-701]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVPAHEKPLM VTKEHIEEVA PLIGEPWMKV GKKIGFTNDE LLFFQMEHPT ANVACVKMLT  60
   61 NWISDDDDAT LENWAYMLEG LEMNKAAEAV KAIIEREKSG STAAFCLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1wxpA
Description: Solution structure of the death domain of nuclear matrix protein p84
Matching Structure (courtesy of the PDB):

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Created and Maintained by: Michael Riffle