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View Structure Prediction Details

Protein: Hpr1-PA
Organism: Drosophila melanogaster
Length: 701 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hpr1-PA.

Description E-value Query
Range
Subject
Range
gi|76651775, gi|... - gi|76651775|ref|XP_870010.1| PREDICTED: similar to THO complex subunit 1 (Tho1) (Nuclear matrix prot...
771.0 [0..10] [691..2]

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Predicted Domain #1
Region A:
Residues: [1-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAVEVANT APEKLANYFA LQSAFEKALE LAITDGKVEL LVKEYNRFPA NTEHDKRLPM  60
   61 DHAFRVLLMK RLDEDVSRIG ELVRLSVEAT RAEIVSNTIP VVLLIDTFDV VTLDKCQKIF 120
  121 QFVEDMVEVW KEEIFFSSCK NNILRMCNDL LRRLSRTQNT VFCGRIQLFL SKFFPFSERS 180
  181 GLNIV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [186-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEFNLDNFTE YGLDSKDHDE SDNKELEDTA EDIPLKIDYD LYCKFWSLQD FFRNPNQCYN  60
   61 KPQWKMFQMH ADNILQSFSS FKLEDVRQSS NENASGTDQA MDVDEEAVD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [295-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTAVSSVIKA NHFFAKFLTN PKLLALQLSD ANFRRAVLVQ FLILFQYLQV SVKFKSDTQT  60
   61 LTADQADFIK ETESRVYKLL EETPPYGKRF SRTVYHMLAR EEMWNNWKNE GCKEFKKPEE 120
  121 PTLSEEDSKP TPNKRPRRPL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [435-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDALRDASRS GKFYLGNDNL TRLWNYSPDN LQACKSEQRN FLPLLETYLE TPHEKVDPAF  60
   61 EWRALRLLAR QTPHFFTSLS QPSSKISDYL EQVRKRLIRD KEPKPAALLS NNSSENNFGL 120
  121 SVNNVHTEGE QDATVALQDG EPEQDLEVED NEPVVEEVD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [594-701]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVPAHEKPLM VTKEHIEEVA PLIGEPWMKV GKKIGFTNDE LLFFQMEHPT ANVACVKMLT  60
   61 NWISDDDDAT LENWAYMLEG LEMNKAAEAV KAIIEREKSG STAAFCLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1wxpA
Description: Solution structure of the death domain of nuclear matrix protein p84
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle