YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: plx-PA
Organism: Drosophila melanogaster
Length: 1379 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for plx-PA.

Description E-value Query
Range
Subject
Range
gi|3893103, gi|7... - pir||T13718 pollux gene protein - fruit fly (Drosophila melanogaster), gi|3893103|emb|CAA76939.1| P...
966.0 [0..1] [1379..1]

Back

Predicted Domain #1
Region A:
Residues: [1-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELMHQMRD PAHTLGGSVG SIPQTLIGGG GGSHGNSNGA LNGIHATPAT NLKMSEAMRN  60
   61 AQHDTSPNPV SSKMKASKSY THGLSSSSGT VNIPTSTSAQ SNLSLLADIS PNHTHFFEVM 120
  121 YVGKIRVSQK RVPNTFIDDA LPKFKAYDAQ RLRLLQNRKM SLSSEGGVGI EAKPSSSLKS 180
  181 HDLKEEDEEE QEQHKGHDDS QDSQAKPLVQ LQLTGAEEGA APRPLEDNKE NKSPEKRPLL 240
  241 RGQSQIELGH KE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [253-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSDGSQPLAA NSQLEAPNVI VNKQPTPPRD QGVGTGTASA SAGPSQLHPN YAMDNIPKQR  60
   61 DRSASQGCIP PYVEQNRTMV FLVGRCDLRL ISPDRKQVLL YKDFKDVASC VHGQKSLDHF 120
  121 GIICRELNND GYIGYVFKCQ SEHVCDDIVA AIAQAFDTCA EQKKKQDTQI FSCEHCPMLW 180
  181 YHKLCTDVEG LSEKKTQALI LRRIETL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.39794
Match: 1wj1A
Description: Solution structure of phosphotyrosine interaction domain of mouse Numb protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.80647115437685 bayes_pls_golite062009
protein binding 2.79653072286066 bayes_pls_golite062009
receptor binding 1.48661693834572 bayes_pls_golite062009
receptor activity 0.391883623216444 bayes_pls_golite062009
enzyme binding 0.226557034609674 bayes_pls_golite062009
integrin binding 0.12314226569467 bayes_pls_golite062009
transmembrane receptor activity 0.0178665883346718 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [460-648]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDDEQEIVWA KFCGSEKTNS PVAEQNQFLM MLLRAHCESR QQRHVHDTAE NRSEFLNQYL  60
   61 GGSTIFMKAK RSLTNSFDNL LKRKPSKDDI AVPSHNLRDI REGSAEPLGT QSPPEGFRSR 120
  121 SNTVGASPSS KPTAEQLKSP MMDIFIKVGN SPKEAETHQG SWRQAILNSV VTPSKGLDSE 180
  181 VPTEFLSPM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [649-799]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKPAKRGKRD AAELRELWRT AIRQTIMLNR METENAMLQA RQNENELKRI KLDYEEIVPC  60
   61 DKQLIERWEQ IIERNSTQIG NKKDPKVLGH AIRTGVPRSK RGDVWTFLAE QHSMNTAPVD 120
  121 TKRFPNFNTP YHMLLKHLTE HQHAIFIDLG R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.522879
Match: 2qq8A
Description: No description for 2qq8A was found.

Predicted Domain #5
Region A:
Residues: [800-1379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFPNHQFYKD PLGLGQLSLF NLLKAYSILD PELGYCQGLG FICGVLLLHC DEANSFQLLK  60
   61 HLMFRRNMRT KYLPDMKKFQ LQLYQLSRLV KDHLPDLYVW LDQNDVSPTL YAAPWILTVF 120
  121 SSQFPLGFVA RVFDLLFLES SDVIFKFAIA LLSVHKQQLL AKDNFEEIMD YLKTVVPKME 180
  181 HTCMEQIMKL VFSMDIGKQL AEYKVEYNVL QEEITTTNHH LEMLNREKTQ NQHLEQQLQF 240
  241 AQSSIAQLET TRSSQQAQIT TLQSQVQSLE LTIQTLGRYV GQLVEHNPDL ELPNEVRRML 300
  301 QQLDDLDRQR RKPIFTERKI GKSVSVNSHL GFPLKVLEEL TERDELGSPQ KQKKEKTPFF 360
  361 EQLRQQQQQH RLNGGGQSSN VGESGSPTPP SRPNRLLDNA SARTVMQVKL DELKLPEHVD 420
  421 KFVANIKSPL EVDSGVGTPL SPPSTASNSS GGSIFSRMGY RTTPPALSPL AQRQSYGVAI 480
  481 TTAPCPQHME EVAPATTMAV MPQEDVEEPQ PMHPLSMVGG DVNVRFKGTT QLKSIRPVHH 540
  541 MRAIPLGGVQ HPSSTEPAVR VAPVPVELAP PAATATTGRS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle