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View Structure Prediction Details

Protein: tacc-PA
Organism: Drosophila melanogaster
Length: 1226 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tacc-PA.

Description E-value Query
Range
Subject
Range
gi|76643965 - gi|76643965|ref|XP_882822.1| PREDICTED: similar to Myosin-8 (Myosin heavy chain, skeletal muscle, pe...
306.0 [0..187] [1225..838]

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Predicted Domain #1
Region A:
Residues: [1-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFDDAENGL GMGFGGRGVL REINKNDGGI KLSPLAVKPS PKPTSMDQQK AMAAALGHQT  60
   61 AVPGGLKPED DLVPKFGGLP EFDETQIPEL APLSTDMDTQ LKSNHSDSDV FVECLSLHSE 120
  121 RYTGDRSELE AYSSALNDVL EQQLSMTSVS TLGAEFNDPL AVSQHNNVSY EAMDVDDLNE 180
  181 TMEML

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [186-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDVLNAEDRH LMQTHILSVT QSKPENNFVH YHPNQEQNRV ELDQLAKHSK PNSDAKESES  60
   61 LVESVLSEES GTQSFEPKLT LSALDSTKDL A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [277-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KHQEEMQTNT KDIFQKEKHH PVSSAQVKDA QNPKEPEKAL NLKEASSELS TKSAKSLEYP  60
   61 NQEKQFSVAV ESMERPCTAI SLEQNASPAM EATEDRTVEE LDQMDVD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [384-622]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESMKVDDATV LNSCRQEQIN AHSPVSSKFF LKLCVQNDTD CQDNKMDQKT AGKESALKMT  60
   61 EIELPVESVP SASLSPPTPA LQAKIIELSL SPPIPTHRPK TAEELEFLAL RELPLPDGVS 120
  121 TAGKVECKQL SHGLVPIVAV LPTPLYLDLK GNTTTASLPE PTSPSFPIKE PAEKQSHFPR 180
  181 SPRAQLEQKD MPYLEEAVVE RSSHRKQSDF GVIAKSPIVF ELTQPSPEKQ HLNETLPMS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [623-787]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EISPTSSNMT FDSGSITEDK SQKGTENIEP SSTLAVSLGS VDDKQRRTFS VVQPTKEEEE  60
   61 AKSRRTFCME NENPRRTFCM QQNASPAVEA TEDTGADEVM DVDISMRADE VAVMKSHQQT 120
  121 WKERQAPISN SPPIPTHQRL NRPPEAISPV SPLGNGTVVL EEQTL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [788-1226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAKEQATLSA SDEKDDVFLE HFGAISPVSD DMFKTSSASN NQAKFRVNAD EETGGKGASA  60
   61 MIRKRSGTAG EQEEIFDAEF HDGVNNQNLI LNSSDFDYLY TKGSNSVPID RSSLLLKFDP 120
  121 LLGAPVPVNH PNQQEQALQN ILGSNQHQNR LLSPTLEEHE TSDGNQSFGV ISSAKDTAKK 180
  181 WDFKPPVDRT KHVKMSVDVI DNDCNKTFDN SNTNTEDKTH NYNDMDELEK KIKNEVTRSE 240
  241 DIEKKLKEGE LREEALIKRI TEKDKTNAKL NGVIEAYEKA IAELISEKEQ QAQLHERQLQ 300
  301 EVQADRDANY HHLTSLETTF SDLHVKYEKS KEMTSQLKSN EESLLAERKQ MMDNLRLQEQ 360
  361 RYDKMKNHAM QQLEIANKKL DTYSREHADE TKKLKALLKK EEISRVSMTE QLQQKSRENA 420
  421 DLLKICEELI YGKGQGGSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.09691
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle