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View Structure Prediction Details

Protein: TBPH-PC, TBPH-PF...
Organism: Drosophila melanogaster
Length: 531 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TBPH-PC, TBPH-PF....

Description E-value Query
Range
Subject
Range
gi|73976771 - gi|73976771|ref|XP_857168.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
312.0 [0..1] [462..72]

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Predicted Domain #1
Region A:
Residues: [1-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFVQVSEEE GDEPIELPAE EDGTLLLSTL QAQFPGSCGL KYRNLDTKAV RGVRSNEGRL  60
   61 FPPSVESGWG EYAYFCVFPK ENKRKSDDNL ENSTAKTKRI ETRLRCTDLI VLGLPWKTTE 120
  121 ESLREYFETY GEVLMAQIKK DTKSGQSKGF GFVRFGSYDA QMRVLTNRHL IDGRWCEVKV 180
  181 PNSKGMGH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.0
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.96087565414382 bayes_pls_golite062009
binding 2.29041217255208 bayes_pls_golite062009
nucleic acid binding 1.91189490017911 bayes_pls_golite062009
mRNA binding 1.52245536665132 bayes_pls_golite062009
protein binding 0.0101134374085809 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [189-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVPCKVFVGR CTEDINSDDL REYFSKFGEV TDVFIPRPFR AFSFVTFLDP DVAQSLCGED  60
   61 HIIKGVSVHV SNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 2adcA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.96087565414382 bayes_pls_golite062009
binding 2.29041217255208 bayes_pls_golite062009
nucleic acid binding 1.91189490017911 bayes_pls_golite062009
mRNA binding 1.52245536665132 bayes_pls_golite062009
protein binding 0.0101134374085809 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [262-373]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APKAEQNRNQ QVQSYNYNSA NSFGMHSYHP QGNHMNPGRN GHHRGNNQHN AHGGENAIVP  60
   61 NNHNIGTAGY GMGGNNYGGN SGGGYHNNGG NHSSGGNTNR QDGGSQYNSR QS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [374-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFHGMNQPHN GNVGGSNGWM NRGHLDMPNL QALGINSQGS SSSNQGQNMS NQSMLNLNSL  60
   61 PINPALVAAA LNQWSLVGNQ LQNQNQDQQG GNFLSWMAQN GGHNNANNFG GRKGPNNPNN 120
  121 NPAANGIKTD NSEPQNGNTG WSNQSSGSQN AAEKSNFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle