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View Structure Prediction Details

Protein: TBPH-PC, TBPH-PF...
Organism: Drosophila melanogaster
Length: 531 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TBPH-PC, TBPH-PF....

Description E-value Query
Range
Subject
Range
gi|73976771 - gi|73976771|ref|XP_857168.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
312.0 [0..1] [462..72]

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Predicted Domain #1
Region A:
Residues: [1-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFVQVSEEE GDEPIELPAE EDGTLLLSTL QAQFPGSCGL KYRNLDTKAV RGVRSNEGRL  60
   61 FPPSVESGWG EYAYFCVFPK ENKRKSDDNL ENSTAKTKRI ETRLRCTDLI VLGLPWKTTE 120
  121 ESLREYFETY GEVLMAQIKK DTKSGQSKGF GFVRFGSYDA QMRVLTNRHL IDGRWCEVKV 180
  181 PNSKGMGH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.0
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.96087565414382 bayes_pls_golite062009
binding 2.29041217255208 bayes_pls_golite062009
nucleic acid binding 1.91189490017911 bayes_pls_golite062009
mRNA binding 1.52245536665132 bayes_pls_golite062009
protein binding 0.0101134374085809 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [189-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVPCKVFVGR CTEDINSDDL REYFSKFGEV TDVFIPRPFR AFSFVTFLDP DVAQSLCGED  60
   61 HIIKGVSVHV SNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 2adcA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.96087565414382 bayes_pls_golite062009
binding 2.29041217255208 bayes_pls_golite062009
nucleic acid binding 1.91189490017911 bayes_pls_golite062009
mRNA binding 1.52245536665132 bayes_pls_golite062009
protein binding 0.0101134374085809 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [262-373]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APKAEQNRNQ QVQSYNYNSA NSFGMHSYHP QGNHMNPGRN GHHRGNNQHN AHGGENAIVP  60
   61 NNHNIGTAGY GMGGNNYGGN SGGGYHNNGG NHSSGGNTNR QDGGSQYNSR QS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [374-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFHGMNQPHN GNVGGSNGWM NRGHLDMPNL QALGINSQGS SSSNQGQNMS NQSMLNLNSL  60
   61 PINPALVAAA LNQWSLVGNQ LQNQNQDQQG GNFLSWMAQN GGHNNANNFG GRKGPNNPNN 120
  121 NPAANGIKTD NSEPQNGNTG WSNQSSGSQN AAEKSNFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle