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View Structure Prediction Details

Protein: inaD-PA
Organism: Drosophila melanogaster
Length: 674 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for inaD-PA.

Description E-value Query
Range
Subject
Range
gi|8896016 - gi|8896016|gb|AAF81203.1|AF245280_1 INAD [Drosophila melanogaster]
320.0 [0..1] [674..1]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQFLGKQGT AGELIHMVTL DKTGKKSFGI CIVRGEVKDS PNTKTTGIFI KGIVPDSPAH  60
   61 LCGRLKVGDR ILSLNGKDVR NSTEQAVIDL IKEADFKIEL EIQTF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1ihjA
Description: Inad
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
signal transducer activity 1.06018756723145 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [106-234]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKSDEQQAKS DPRSNGYMQA KNKFNQEQTT NNNASGGQGM GQGQGQGQGM AGMNRQQSMQ  60
   61 KRNTTFTASM RQKHSNYADE DDEDTRDMTG RIRTEAGYEI DRASAGNCKL NKQEKDRDKE 120
  121 QEDEFGYTM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.34
Match: 1x6dA
Description: Solution structures of the PDZ domain of human Interleukin-16
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [235-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKINKRYNMM KDLRRIEVQR DASKPLGLAL AGHKDRQKMA CFVAGVDPNG ALGSVDIKPG  60
   61 DEIVEVNGNV LKNRCHLNAS AVFKNVDGDK LVMITSRRKP NDEGMCVKPI KKFPTASDET 120
  121 KFIFDQFPKA RTVQVRKEGF LGIMVIYGKH AEVGSGIFIS DLREGSNAEL AGVKVGDMLL 180
  181 AVNQDVTLES NYDDATGLLK RAEGVVTMIL LTLKSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 1ky9A
Description: Protease Do (DegP, HtrA), C-terminal domains; Protease Do (DegP, HtrA), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [451-674]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAIKAEKAAE EKKKEEAKKE EEKPQEPATA EIKPNKKILI ELKVEKKPMG VIVCGGKNNH  60
   61 VTTGCVITHV YPEGQVAADK RLKIFDHICD INGTPIHVGS MTTLKVHQLF HTTYEKAVTL 120
  121 TVFRADPPEL EKFNVDLMKK AGKELGLSLS PNEIGCTIAD LIQGQYPEID SKLQRGDIIT 180
  181 KFNGDALEGL PFQVCYALFK GANGKVSMEV TRPKPTLRTE APKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1u3bA
Description: Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains
Matching Structure (courtesy of the PDB):

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