| Protein: | cv-2-PA |
| Organism: | Drosophila melanogaster |
| Length: | 751 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cv-2-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
247.0 | [0..1] | [751..1] |
|
Region A: Residues: [1-96] |
1 11 21 31 41 51
| | | | | |
1 MCCQSSGQWK FPAQQPRKSL ASRRRHTGFR PSTQLLILIA VLLALLQGRT VDAGAGDSLS 60
61 GVRQSCSNEG EEVQLKNQPQ IFTCFKCECQ NGFVNC
|
| Detection Method: |  |
| Confidence: | 6.522879 |
| Match: | 1tozA |
| Description: | NMR structure of the human NOTCH-1 ligand binding region |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [97-513] |
1 11 21 31 41 51
| | | | | |
1 RDTCPPVNDC YILDKSNGTC CRRCKGCSFR GMSYESGSEW NDPEDPCKTY KCVATVVTET 60
61 IQKCYSQCDN NQLQPPRPGE CCPTCQGCKI NGQTVAEGHE VDASIDDRCL VCQCRGTQLT 120
121 CSKKTCPVLP CPMSKQIKRP DECCPRCPQN HSFLPVPGKC LFNKSVYPEK TQFMPDRCTN 180
181 CTCLNGTSVC QRPTCPILEC APEFQEPDGC CPRCAVAEVR SECSLDGIVY QNNETWDMGP 240
241 CRSCRCNGGT IRCAQMRCPA VKCRANEELK QPPGECCQRC VETAGTCTVF GDPHFRTFDG 300
301 KFFSFQGSCK YLLASDCMGK TFHIRLTNEG RGTRRASWAK TVTLSLRNLK VNLGQRMRVK 360
361 VNGTRVTLPY FVVAGGQNVT IERLANGGAV MLRSEMGLTL EWNGAGFLQV SVPAKFK
|
| Detection Method: | |
| Confidence: | 7.69897 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor binding | 4.60755835611133 | bayes_pls_golite062009 |
| growth factor activity | 4.38305031783896 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 3.49243532917035 | bayes_pls_golite062009 |
| heparin binding | 3.0535264040722 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 2.92645080817676 | bayes_pls_golite062009 |
| polysaccharide binding | 2.79319890241656 | bayes_pls_golite062009 |
| binding | 2.07793256968292 | bayes_pls_golite062009 |
| pattern binding | 1.7855850180475 | bayes_pls_golite062009 |
| protein binding | 1.71989387545809 | bayes_pls_golite062009 |
| carbohydrate binding | 0.75634551012462 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 0.65339109098708 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 0.6530199085873 | bayes_pls_golite062009 |
| transcription factor binding | 0.556175571276939 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 0.470263535896705 | bayes_pls_golite062009 |
|
Region A: Residues: [514-595] |
1 11 21 31 41 51
| | | | | |
1 KRLCGLCGNF NGSSRDDLTG KDGRSHGDDE VWHFANSWKV GGPKSCSRKR EFLAATPTCD 60
61 KRKSNFYCHP LSVPALFGEC NE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [596-751] |
1 11 21 31 41 51
| | | | | |
1 RLNPENYKAA CRMDVCECPS GDCHCDSFAA YAHECRRLGV QLPDWRSATN CPAGWRRNAT 60
61 LSSFKGNQFY GDPSFSRMKG RRQKNHQLRL QLQQEQQQRS KQGQKGRHKP GGHNQLDRQG 120
121 HNGLDKDQLQ KEFILKHVPS SFLYPRAPDR TPPPLH
|
| Detection Method: | |
| Confidence: | 1.67 |
| Match: | 1couA |
| Description: | Anticoagulant protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.5247816153916 | bayes_pls_golite062009 |
| protein binding | 0.833726797288547 | bayes_pls_golite062009 |
