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View Structure Prediction Details

Protein: sm-PB
Organism: Drosophila melanogaster
Length: 404 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sm-PB.

Description E-value Query
Range
Subject
Range
gi|76689281 - gi|76689281|ref|XP_881384.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
262.0 [0..5] [391..20]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNLNANASA FLWQVPPPQQ LTPQSVQQQT VQSVQSMQSV QHSQLLQSAV VSQPRKFGGN  60
   61 KSNYNYMQNH AIMGPGGGPM GGIGGNPNIY RKRHSINTYN AGLYQTNEPP LLGPGAAFPP 120
  121 FGAPEYHTTT PENWKGAAIH P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.154902
Match: 2adbA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [142-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGLMKEPAGV VPGRNAPVAF TPQGQAQGAV MMVYGLDHDT SNTDKLFNLV CLYGNVARIK  60
   61 FLKTKEGTAM VQMGDAVAVE RCVQHLNNIP VGTGGKIQIA FSKQNFLSEV INPFLLPDHS 120
  121 PSFKEYTGSK NNRFLSPAQA SKNRIQPPSK ILHFFNTPPG LTEDQLIGIF NIKDVPATSV 180
  181 RLFPLKTERS SSGLIEFSNI SQAVLAIMKC NHLPIEGKGT KFPFIMKLCF SSSKSMNGAW 240
  241 NNAASEGMIE KENEVDTKVD IYN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.09691
Match: 2adcA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
4.67888641618755 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.49612884560266 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
snRNA binding 1.76821382294389 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
protein binding 1.14508556628804 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
U1 snRNA binding 0.612226940931031 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009
transporter activity 0.00947930769815086 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle