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View Structure Prediction Details

Protein: Rep-PA
Organism: Drosophila melanogaster
Length: 511 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rep-PA.

Description E-value Query
Range
Subject
Range
gi|4324461 - gi|4324461|gb|AAD16891.1| Rab escort protein homolog [Drosophila melanogaster]
328.0 [0..1] [511..1]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDDLPEQFD LVVIGTGFTE SCIAAAGSRI GKSVLHLDSN EYYGDVWSSF SMDALCARLD  60
   61 QEVEPHSALR NARYTWHSME KESETDAQSW NRDSVLAKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1i8tA
Description: UDP-galactopyranose mutase, N-terminal domain; UDP-galactopyranose mutases
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [100-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRFSLDLCPR ILYAAGELVQ LLIKSNICRY AEFRAVDHVC MRHNGEIVSV PCSRSDVFNT  60
   61 KTLTIVEKRL LMKFLTACND YGEDKCNEDS LEFRGRTFLE YLQAQRVTEK ISSCVMQAIA 120
  121 MCGPSTSFEE GMQRTQRFLG SLGRYGNTPF LFPMYGCGEL PQCFCRLCAV YGGIYCLKRA 180
  181 VDDIALDSNS NEFLLSSAGK TLRAKNVVSA PGYTPVSKGI ELKPHISRGL FISSSPLGNE 240
  241 ELNKGGGGVN LLRLLDNEGG REAFLIQLSH YTGACPEGLY IFHLTTPALS EDPASDLAIF 300
  301 TSQLFDQSDA QIIFSSYFTI AAQSSKSPAA EHIYYTDPPT YELDYDAAIA NARDIFGKMF 360
  361 PDADFLPRAP DPEEIVVDGE DPSALNEHTL PEDLRAQLHD MQQATQEMDI QE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.0
Match: 1ltxR
Description: Rab escort protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
Rab geranylgeranyltransferase activity 9.99062899455963 bayes_pls_golite062009
protein prenyltransferase activity 9.51472596751319 bayes_pls_golite062009
protein geranylgeranyltransferase activity 9.04655134250827 bayes_pls_golite062009
prenyltransferase activity 7.67724812902621 bayes_pls_golite062009
small GTPase regulator activity 1.82777033221452 bayes_pls_golite062009
GTPase regulator activity 1.69589677829425 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.67690582043816 bayes_pls_golite062009
transporter activity 1.29839290134235 bayes_pls_golite062009
binding 1.28745887296004 bayes_pls_golite062009
transmembrane transporter activity 1.07862908893913 bayes_pls_golite062009
catalytic activity 1.03127962968326 bayes_pls_golite062009
enzyme regulator activity 1.00883251592654 bayes_pls_golite062009
amine oxidase activity 0.93095855430028 bayes_pls_golite062009
substrate-specific transporter activity 0.556967966402473 bayes_pls_golite062009
nucleic acid binding 0.450613852654832 bayes_pls_golite062009
GDP-dissociation inhibitor activity 0.387378304822822 bayes_pls_golite062009
protein binding 0.347133050347128 bayes_pls_golite062009
transcription regulator activity 0.317465086590155 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.31459693204333 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 0.2899722058349 bayes_pls_golite062009
transferase activity 0.240250859292614 bayes_pls_golite062009
DNA binding 0.175917747732026 bayes_pls_golite062009
Rab GTPase binding 0.152281351170071 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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