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View Structure Prediction Details

Protein: ssp4-PA
Organism: Drosophila melanogaster
Length: 1517 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ssp4-PA.

Description E-value Query
Range
Subject
Range
gi|28317277 - gi|28317277|gb|AAO39638.1| AT18914p [Drosophila melanogaster]
896.0 [0..1] [1517..1]

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Predicted Domain #1
Region A:
Residues: [1-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVETQEIRQ ARQRASVKWL LSKAFNNRVP DNLKEPFYRD HENQERLKPQ IIVELGNATL  60
   61 YCQTLANLYS DPNYQSMNHW SIIQTLARKG VPVAESADMP ITETVLIQTN PLRINAHMSV 120
  121 IESLMVLYAK EISSGDRVMA AIRRISGNNY QAPTGQSYEQ ALLGWISHAC AALKKRIIKE 180
  181 VDAGLPDDNG SRLQTPDIPP VRDFQDLCDG ICLALLISYY CPKVVPWTSV RINYLPAVED 240
  241 SIHNILLVCN FSQKHLPYTV MHMTPEDVTY MRGSMKLNLV VLLTDLFNLF EIHPAKCVCY 300
  301 PG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.26
Match: 1sh5A
Description: Crystal structure of actin-binding domain of mouse plectin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 6.0562477479739 bayes_pls_golite062009
microtubule binding 5.63808442303747 bayes_pls_golite062009
tubulin binding 5.63161872515663 bayes_pls_golite062009
actin binding 5.4843525466095 bayes_pls_golite062009
actin filament binding 3.58546515893973 bayes_pls_golite062009
binding 2.58893177478913 bayes_pls_golite062009
protein binding 2.38389820189848 bayes_pls_golite062009
microtubule plus-end binding 2.34204492212228 bayes_pls_golite062009
structural constituent of cytoskeleton 2.33067686982903 bayes_pls_golite062009
dynein binding 0.282231591450947 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [303-1181]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGQVPHSNS FGGGLNRRST PPNEYQTVQS NNFDGNHAEA FVVHKSRGIT TLASMHSQQQ  60
   61 QQLHQQQQHQ QQYHQQPLQQ HPSQSQLQIQ QQEPLVPARL RQAKEKTNVE SKADERGDFV 120
  121 AAGRPSNWEQ SRRPSFAGRR SRRNSSSEDS QLTIENFGGS QDQLNTLGRY ERDRERKLSN 180
  181 TSVGSYPVEP AVAVRSSIAD ARGTLQLGYD TDSGSEKQDR ETEKYSMRRQ VSVDNVPTVS 240
  241 SHNLSNAGSP LPVARHKQHS SDKDYSSNSG MTPDAYNDSR STSGYDPEST PVRKSSTSSM 300
  301 PASPAAWQLD VGDDDMRSLE NASKLSTIRM KLEEKRRRIE QDKRKIEMAL LRHQEKEDLE 360
  361 SCPDVMKWET MSNESKRTPD MDPVDLDKYQ AYNAPVSAYS SRPPSRDPYQ QQLHHQQQQP 420
  421 MPMPQPMQYV NEHGQYMSPP QPAHYMPQQA QQPQSIYSDN GAAYNHSNHS PYGGTPQYRS 480
  481 SVVYDDYGQP TNHFYLHESS PQPQAHQHPQ RRTWAHSAAA AAYEQQQQIQ PSLVDVNAWQ 540
  541 TQQHQKQKQT WMNRPPSSAG APSPGSFMLH QNGGGGGGGG GGGELQHLFQ VQASPQHGQR 600
  601 QVSGSNGVQR QQSLTNLRDN RSPKAPQNMG MPMGMPMQQE DMMAPQSICF IGDEEDVDEL 660
  661 ERNIIESMQS THISDFVHQQ QQQHQHQQQL QQQQRLQGHS GRGSSSEDYD SGEMISNKLN 720
  721 ITSGNLTYRI PSPSRPSIQA NSFQDPRAMA AASGGEDQPP EKGFYISFDD EQPKRPKPPL 780
  781 RAKRSPKKES PPGSRDSVDN QATLKRESLS HLHNNNNIGF GNDDVNSKPV TRHSIHGLNN 840
  841 SNSVKSPGNA TYNKYTDEPP IQLRQLAVSG AMSPTSNER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1y0fA
Description: No description for 1y0fA was found.

Predicted Domain #3
Region A:
Residues: [1182-1432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HHLDDVSNQS PQQTQQPMSP TRLQQSSNNA EAAKNKALVI GADSTNLDPE SVDEMERRKE  60
   61 KIMLLSLQRR QQQEEAKARK EIEASQKREK EREKEEERAR KKEEQMARRA AILEQHRLKK 120
  121 AIEEAEREGK TLDRPDLHVK LQSHSSTSTT PRLRQQRTTR PRPKTIHVDD ASVDISEASS 180
  181 ISSRGKKGSS SNLTGPKLYK QPAAKSNRGI ILNAVEYCVF PGVVNREAKQ KVLEKIARSE 240
  241 AKHFLVLFRD A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [1433-1517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GCQFRALYSY QPETDQVTKL YGTGPSQVEE VMFDKFFKYN SGGKCFSQVH TKHLTVTIDA  60
   61 FTIHNSLWQG KRVQLPSKKD MALVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.09691
Match: 1ugjA
Description: Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16
Matching Structure (courtesy of the PDB):

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