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View Structure Prediction Details

Protein: Lac-PA
Organism: Drosophila melanogaster
Length: 359 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Lac-PA.

Description E-value Query
Range
Subject
Range
ROBO1 - roundabout, axon guidance receptor, homolog 1 (Drosophila)
280.0 [0..26] [359..65]

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Predicted Domain #1
Region A:
Residues: [1-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWRPSISNCV WSTLLLAIFV QQTLAQRTPT ISYITQEQIK DIGGTVEFDC SVQYAKEYNV  60
   61 LFLKTDSDPV FLSTGSTLVI KDSRFSLRYD PNSSTYKLQI KDIQETDAGT YTCQVVISTV 120
  121 HKVSAEVKLS VRRPPVISDN STQSVVASEG SEVQMECYAS GYPTPTITWR RENNAILPTD 180
  181 SATYVGNTLR IKSVKKEDRG TYYCVADNGV SKGDRRNINV EVEFAPVITV PRPRLGQALQ 240
  241 YDMDLECHIE AYPPPAIVWT KDDIQLANNQ HYSISHFATA DEYTDSTLRV ITVEKRQYGD 300
  301 YVCKATNRFG EAEARVNLFE TIIPVCPPAC GQAYIAGAED VSATSFALVG ILAALLFAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.0
Match: 1cs6A
Description: Axonin-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.33804459527604 bayes_pls_golite062009
receptor activity 1.90298241148243 bayes_pls_golite062009
signal transducer activity 1.59395248964472 bayes_pls_golite062009
molecular transducer activity 1.59395248964472 bayes_pls_golite062009
transmembrane receptor activity 1.5023290800351 bayes_pls_golite062009
fibroblast growth factor 1 binding 1.39482409678992 bayes_pls_golite062009
cell adhesion molecule binding 1.36789541796983 bayes_pls_golite062009
fibroblast growth factor receptor activity 1.13671712991988 bayes_pls_golite062009
protein binding 1.0782734177126 bayes_pls_golite062009
fibroblast growth factor binding 0.646668003618218 bayes_pls_golite062009
integrin binding 0.599569390248921 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle