YRC Public Data Repository - Protein Structure Prediction

Protein:	CG12909-PA
Organism:	Drosophila melanogaster
Length:	281 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG12909-PA.

Description	E-value	Query Range	Subject Range
gi\|34849506, gi\|... - gi\|41053431\|ref\|NP_956973.1\| Ly1 antibody reactive homolog [Danio rerio], gi\|34849506\|gb\|AAH58310.1\|...	260.0	[0..1]	[279..1]
gi\|21536909 - gi\|21536909\|gb\|AAM61241.1\| unknown [Arabidopsis thaliana]	249.0	[0..1]	[281..1]
gi\|39581890, gi\|... - gi\|39581890\|emb\|CAE72852.1\| Hypothetical protein CBG20151 [Caenorhabditis briggsae], gi\|187023628\|em... gi\|157776197 - gi\|157776197\|ref\|XP_001666164.1\| hypothetical protein CBG20151 [Caenorhabditis briggsae AF16]	249.0	[0..1]	[279..1]
CE01499 - cell growth regulating protein status:Confirmed UniProt:Q09464 protein_id:CAA86746.1	234.0	[0..1]	[280..1]
gi\|115437932, gi... - gi\|115437932\|ref\|NP_001043416.1\| Os01g0583200 [Oryza sativa (japonica cultivar-group)], gi\|113532947...	228.0	[0..1]	[281..19]
gi\|54635998, gi\|... - gi\|54635998\|gb\|EAL25401.1\| GA11899-PA [Drosophila pseudoobscura], gi\|125808676\|ref\|XP_001360826.1\| G...	220.0	[0..1]	[278..1]
gi\|26345614 - gi\|26345614\|dbj\|BAC36458.1\| unnamed protein product [Mus musculus]	210.0	[0..1]	[183..1]

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Predicted Domain #1

Region A:
Residues: [1-63]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFFTCNICG ESVKKPAVEK HYQTRCRGKD KNVSCMDCLK DFYGEEYVAH IKCISEAQKY  60
   61 ASQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.154902
Match:	1wjvA
Description:	Solution structure of the N-terminal zinc finger domain of mouse cell growth regulating nucleolar protein LYAR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.75384162940108	bayes_pls_golite062009
nucleic acid binding	1.57776971811162	bayes_pls_golite062009
DNA binding	1.44675129642632	bayes_pls_golite062009
transcription regulator activity	1.20428473898846	bayes_pls_golite062009
transcription factor activity	0.35678698773089	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [64-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQGFAAKEPR NKNAQKQESW MDIIRSILDS SEYNLTPAVR SAFQKLQSVD NVPRKKAKFE  60
   61 NFVGNCMRMP RNQATQVWDI LEKELNKMKE AKQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [157-281]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AELARAKAEK IAEIQQKQKA EVEEEAPPKK KAKVETTEDA AAEETSNGVT SDFDWAAQLT  60
   61 KIVTKQADGI FLEKLRKKLL KKYAKHLSVE DLNEKQAKKF QKRFDKQLKL ADSLEVEGEI 120
  121 VKIAS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: