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View Structure Prediction Details

Protein: ced-6-PC, ced-6-...
Organism: Drosophila melanogaster
Length: 517 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ced-6-PC, ced-6-....

Description E-value Query
Range
Subject
Range
gi|54636724, gi|... - gi|54636724|gb|EAL26127.1| GA11210-PA [Drosophila pseudoobscura], gi|125810625|ref|XP_001361549.1| G...
328.0 [0..1] [517..1]

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Predicted Domain #1
Region A:
Residues: [1-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYQPANSGG TSGGSKAAAK MAQLKFWNKQ NSSKQQQQDK DKDAADGGNN TSGGGTGSNS  60
   61 NGDAKSEAKN GKRNWLHTPE QLISGHAVYL VKFFGNLSVD QPKGIEVVKE AIRKLQFAQQ 120
  121 MKKAETGTQE KFKKLEITIS IKGVAIQEPR THKILHQFPL YNISYCADEK GVKKFFSFIA 180
  181 KTVKTQDGSD PTSNGHANGN GDGSAKVEES HECFVFISNK LASDITLTIG QAFDLAYRKY 240
  241 MDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.221849
Match: 1n3hA
Description: Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.5144141194236 bayes_pls_golite062009
protein binding 1.42613583294271 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [244-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEKTNLSKAQ QQINHLQQTV NVYKERLREV SAKLPKAELD ALLFNLGIKD ILEAPTTEPQ  60
   61 NGIEVASEAL SNGKLDDDKL LIDTNSTTAS THSASPSSFL PIVPPRNNLS SQISIGGKSN 120
  121 SQKMDELLLN SDSDSDFDPR ADETQEIGGT GRSAISNMFG FEPANSFGQH LFSNNNDHKL 180
  181 QNNNSSLLIT SNNNSINSSG FSSELNITPP LLAPPPKIAA PRRLNSVTTG NGLNGNTDLF 240
  241 GSDPFELNNG PNIFKQNQLN LDDFSLESLD PLRK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle