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View Structure Prediction Details

Protein: Rme-8-PA
Organism: Drosophila melanogaster
Length: 2408 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rme-8-PA.

Description E-value Query
Range
Subject
Range
gi|125810791, gi... - gi|54636805|gb|EAL26208.1| GA20767-PA [Drosophila pseudoobscura], gi|125810791|ref|XP_001361629.1| G...
3337.0 [0..1] [2408..1]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPPKENVDL ECFLVTKHSW KGRYKRILSI GTAGISTYNP DKLDLTNRWS YSDIVAAAPS  60
   61 KTTNIPHDFV ITIKKDKKLD TIKLSSEYRN DILSSILKYY KEFADK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [107-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKNAQRFSAY KYHWSGISLP TVLEVTPCSL DQLDPTTNDV LASYMYKDIE GIIAGISDYE  60
   61 GGIVMAYGGF SRLHLFKALN HHEIVQNIAQ RSAQFLGIET KILKSQITLE QFERQRFGKF 120
  121 SGDQFQTSST EFSVHKITPR HP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [249-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPVKRILCLT EVTLLERDPQ TYSVCTLRPL TDVFALVRDK DNLQRFSIEY KNGIVRNYST  60
   61 NDRDSLLATV LDAVRSSGN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [328-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDVHVRIGNT PRGKRYVPLN SSVDEETEAN LMRLVINNFQ NPSKRYEILE RFNANVPHSG  60
   61 LNYSVTQDSL FAENKDKLIL SALQALAQKE LDSPTAQLSN LELEAIFHAL TRLLASKVGY 120
  121 AAFTNLPGFR EIIGTKVVAA LRRKDLAVTY SAIDMINSLM H

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [489-630]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVNSDHDLKQ EQLNKSSILS SKSFLETLLN MWTTHVSHGS GALVLSAMLD FMTFALCVPY  60
   61 SETTDGKQFD TLLELVADRG RYLYKLFQHP SLAIVKGAGL VLRAIIEEGE LQVAQQMQAL 120
  121 ALDEAALCRH LLVALYTPSN DP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [631-861]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQTTQRQLSR HLIGLWLTDS EEAMELFKRI FPAGLLTFLE SEETVPESDV EEDKLNFRDN  60
   61 LKFAIQHSNK TRKNVIEKHL QGIKHWGMNL IEKQDGAAQA LKNRPVVLRN RRQKKKTSDV 120
  121 VVNLPFFFYS FAKDHSLPNL IWNHKTREEL RMCLENELRQ FLNDRDLAGQ MIVAWNYQEF 180
  181 EVAYQCLADE IKIGDYYIRL ILEKDDWPQN LVKDPIELFN ALYRRVLCRQ R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [862-955]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNDDQMTVFS LQALAKVYRR YHAEIGKFND MSYILQLSDR CLSPSMRDAL INLISCLVLE  60
   61 KSNSRALIDH VQCLVDLITL AHLHKGRAQL NTKT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [956-1037]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVIEAGPNMG TYEEKDWYYN IEKDGQKPER QGPITYSELK ELWQKGLITP KTRCWAIGMD  60
   61 GWRSLQQIPQ LKWCLIAKGT PL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1038-1294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDETELSSKI LDILIKCTSF FPSRTQNGVA VLIPGPKLSR KLSEFICLPH VVQVCLTHDP  60
   61 GLLERVATLL YQIMEDNPEM PKVYLTGVFY FMLMYTGSNI LPITRFLKMT HMKQGFRSEE 120
  121 TSQSGIMHRS ILGQLLPEAM VCFLENYSAE KFAEIFLGEF DTPEVIWSSE MRRLLIEKIA 180
  181 AHIADFTPRL RGHTMARYPY LAIPVISYPQ LENELFCHIY YLRHLCDTQK FPNWPISDPV 240
  241 QLLKHTLDAW RKEVEKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1295-1405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPQMTIQQAY QDLGIDLTKT PKPDESMIRK SYYKLAQMYH PDKNPNGREI FEKVNQAYEF  60
   61 LCSRNVWSSG GPDPNNIVLI LRTQSILFER YPDVLRPYKY AGYPQLIKTI R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.0
Match: 1xblA
Description: NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.58214482002828 bayes_pls_golite062009
protein binding 1.37672975699838 bayes_pls_golite062009

Predicted Domain #11
Region A:
Residues: [1406-1621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LETRDDELFS KEAQLLTAAS ELCYHTVHCS ALNAEELRRE EGIEALLEAY TRCVSILGVD  60
   61 SKPDSLHYQV ISNVTRCFEV ACNFEKCKQK IIQLPQLLSD VCRVVYFKHT LSVSLVTSLA 120
  121 ANNYDLQCQL SRNGVLWSLL LFIFEYDYTL DESGVDVSDK SNQQQLANNL AKMAVLGCIA 180
  181 LAGYSMELRQ KPVTGSETNS PAAKAPPVIK PKPSVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 1nltA
Description: The crystal structure of Hsp40 Ydj1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.68064826625864 bayes_pls_golite062009
protein binding 1.3466202387299 bayes_pls_golite062009

Predicted Domain #12
Region A:
Residues: [1622-1774]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AASSSTYTQN AHNPLQSKQL AITSGKEKES DTSSGSSDTA SSTPTESEQQ QQLTKTRTSA  60
   61 IQQKYIVTGE AKNSLIKQVL DRLLTRYISN QLATVRDSDV LKLLTANTRN PYLIWDNGTR 120
  121 AQLKDFLEQQ RTASAKETHE DIAQVSELVS SFE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #13
Region A:
Residues: [1775-1828]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDAHKDELQI GGIFIRIYND MPTHPIAQPK LFIMDLLEYL KHAYQFLQYK KNPA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #14
Region A:
Residues: [1829-2055]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STAAPVNATP KMGNDGILTP TLAPNHPQLQ QASTGKSGTT FDEVLTAYNR SKSRKKLETD  60
   61 ALTEQQLALQ QSKYDFSSDG KIELHITMVL KALIAVIKAN AEVEIQCIGN FDMIFGFLAS 120
  121 NIFPDNSTVK AVALEVVSLV SRNKECVSEV AACEILGNYL VALKDPELRA SQVKVLETLS 180
  181 GLMNVQEMIK EAQAKGATIY LLDMFCNSRN PQIREMCAGI LAKMTAD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #15
Region A:
Residues: [2056-2132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLSGPKVRIT VSKFLPALFI DAMVESPATS VQLFESIHEH PELIWNDTTR SNVCDAVADT  60
   61 CQRFYQLQKA NSRHVWK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #16
Region A:
Residues: [2133-2294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPEILKDIVS NEIVVAGVYL RLFVSNPAWT LRKPKQFLSD LLDFVVEQIG KSSSEQDVLD  60
   61 LSTTALVELL RSQPNLADDI PVLGHIPKLF NLLSVQPKNT LSVLHQLSLS EFCVSAISQT 120
  121 ECVAPLKKCM EHNRDCIEKA CEALSRLFKH QHDSLISQSL EV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #17
Region A:
Residues: [2295-2408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLIPFLLGLL DSRLEFVDNP SAVKAQIVAA LKGMTHNLNY GDRVTQILLK HPVWAEFKDQ  60
   61 RHDLFIADTT IRGYLTGVNP TAGYLTAGPA QSVEVLTSPP PIDRDDPSAR PPID

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle